Uncertainty makes scientific research challenging and at the same time exciting. Whereas curiosity and passion for uncovering the unknown drive future generations of researchers, the landscape of science has changed. We investigated whether the requirements for having a successful research career are changing, and whether junior researchers are aware of these requirements. Structured discussion with peers and more experienced researchers can point the way forward to an excellent career.
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http://dx.doi.org/10.1038/ng.2527 | DOI Listing |
Plants (Basel)
January 2025
School of Architecture and Urban Planning, Anhui Jianzhu University, Hefei 230601, China.
The frequent occurrence of extreme weather conditions in the world has brought many unfavorable factors to plant growth, causing the growth and development of plants to be hindered and even leading to plant death, with abiotic stress hindering the growth and metabolism of plants due to severe uncontrollability. The WHY1 transcription factor plays a critical role in regulating gene expression in plants, influencing chlorophyll biosynthesis, plant growth, and development, as well as responses to environmental stresses. The important role of the gene in regulating plant growth and adaptation to environmental stress has become a hot research topic.
View Article and Find Full Text PDFBiomedicines
January 2025
Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.
: Genes and environments were transmitted across generations. Parents' genetics influence the environments of their offspring; these two modes of inheritance can produce a genetic nurture effect, also known as indirect genetic effects. Such indirect effects may partly account for estimated genetic variance in T2D.
View Article and Find Full Text PDFBMC Public Health
January 2025
Saw Swee Hock School of Public Health, National University of Singapore, Tahir Foundation Building, 12 Science Drive 2, Level 09-03J, Singapore, 117549, Singapore.
Background: Enabling community-led health initiatives will contribute to reducing the burdens on the healthcare system. Implementing such initiatives successfully in high and upper-middle income Asian countries is poorly understood and documented. We undertook a Rapid Review, systematically synthesising the evidence to develop implementation guidelines to address this gap.
View Article and Find Full Text PDFBMC Genom Data
January 2025
Anhui Province Key Laboratory of Pollution Damage and Biological Control for Huaihe River Basin, Fuyang Normal University, Fuyang, 236037, China.
Objective: Clonostachys, a genus with rich morphological and ecological diversity in Bionectriaceae, has a wide distribution among diverse habitats. Several studies have reported Clonostachys fungi as effective biological agents against multiple fungal plant pathogens. To clarify the diversity and biocontrol mechanisms of the Clonostachys fungi, this study was undertaken to sequence and assemble the genomes of two C.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Anorectal Surgery, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Introduction: Intestinal constipation is a substantive global health concern, significantly impairing patient quality of life. An emerging view is that the gut microbiota plays a critical role in intestinal function, and probiotics could offer therapeutic benefits. This study aims to consolidate evidence from randomized controlled trials (RCTs) that assess the effectiveness of probiotics in modulating microbiota and ameliorating symptoms of constipation.
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