AI Article Synopsis

  • - Six strains of multiresistant Klebsiella pneumoniae, which produce the NDM-1 enzyme, were found during an outbreak affecting neonatal patients in a Colombian hospital.
  • - Molecular examination revealed that all strains contained the blaNDM-1, qnrA, and intI1 genes and shared a close genetic relationship.
  • - These strains represent a new sequence type (ST1043) never documented before, marking the first identification of NDM-1-producing bacteria in South America.

Article Abstract

Six multiresistant, NDM-1-producing Klebsiella pneumoniae strains were recovered from an outbreak that affected six neonatal patients in a Colombian hospital. Molecular analysis showed that all of the isolates harbored the blaNDM-1, qnrA, and intI1 genes and were clonally related. Multilocus sequence typing showed that the isolates belonged to a new sequence type (ST1043) that was different from the sequence types that had previously been reported. This is the first report of NDM-1-producing isolates in South America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623329PMC
http://dx.doi.org/10.1128/AAC.01447-12DOI Listing

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