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[Efficacy and safety of topical antibiotic therapy in patients with acute external bacterial otitis: results of a retrospective study].
Vestn Otorinolaringol
December 2024
Sverzhevsky Research Clinical Institute of Otorhinolaryngology, Moscow, Russia.
Otitis externa is one of the most common diseases in otorhinolaryngological practice frequently requiring prescription of analgesic medications and antimicrobials. The total of 2714 patients were included in the retrospective study to evaluate bacterial etiology, effectiveness, and safety of topical empirical treatment of patients with diagnosed otitis externa during 2018-2023. The most common pathogens isolated were (38.
View Article and Find Full Text PDFReevaluating the Causes of Otitis Externa: A Case Report.
Cureus
November 2024
Department of Otorhinolaryngology, Woodlands Health Campus, Singapore, SGP.
A 28-year-old female domestic helper presented to the Ear, Nose, and Throat clinic complaining of three weeks of right otalgia associated with a right blocked ear. The hearing was otherwise normal, and she denied otorrhoea, dizziness or imbalance, ear digging, or water contact, and has no history of ear eczema. She has no other past medical history and no recent travel history.
View Article and Find Full Text PDFAlterations of Sensory-related Functional Brain Network Connectivity in Homozygous Knockout Mice.
Phenomics
October 2024
Human Phenome Institute, Institute of Medical Genetics and Genomics, MOE Key Laboratory of Contemporary Anthropology, Zhangjiang Fudan International Innovation Center, Fudan University, 825 Zhangheng Road, Shanghai, 201203 China.
Unlabelled: () is a neuro-specific gene linked to neurodevelopmental disorders and has recently been reported to function as a bidirectional emotional regulator, highlighting its molecular roles in the nervous system. However, the connections between , brain architecture, and functionality remain to be fully elucidated. Our study utilized 11.
View Article and Find Full Text PDFDEK::AFF2 fusion-associated middle ear non-keratinizing squamous cell carcinoma: A case report.
World J Clin Oncol
December 2024
Department of Pathology, Peking University People's Hospital, Beijing 100044, China.
Background: Primary squamous cell carcinoma (SCC) of the middle ear is rare, with non-keratinizing basaloid types being exceptionally uncommon. Distinguishing these cancers, often caused by viral factors (, human papillomavirus or Epstein-Barr virus), or specific genetic alterations (, bromodomain-containing protein 4-nuclear protein in or gene fused with FLI chromosomal rearrangement), from other cranial conditions, is difficult. The recently identified DEK::AFF2 non-keratinizing SCC (NKSCC) is a novel subtype, fitting the World Health Organization classification of head and neck neoplasms.
View Article and Find Full Text PDFLaser Ablation of an Isolated External Auditory Canal Skin Wedge.
Ann Otol Rhinol Laryngol
December 2024
Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, MN, USA.
Introduction: External ear malformations represent a spectrum of congenital anomalies that may involve the external auditory canal (EAC), tympanic membrane (TM), or associated structures. A rare anomaly, the EAC skin wedge, results from incomplete canalization during embryologic development. This report presents the clinical presentation, diagnostic evaluation, and surgical management of this condition.
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