Background: The usefulness of positron emission tomography (PET) with fluorine-deoxyglucose (FDG) in sarcomas and non-sarcoma non-epithelial (NSNE) tumors is not clearly defined.
Aim: To report a Chilean experience with NSNE tumors evaluated using PET with FDG.
Material And Methods: Retrospective review of the database of a PET laboratory. Demographic data, indications and metabolic findings were compared with conventional imaging in 88 adults and children with diverse bone and soft tissue sarcomas as well as 24 gastrointestinal stromal tumors (GIST), 6 pleural malignant mesotheliomas in adults, and 9 medulloblastomas in children.
Results: FDG showed good concordance with conventional imaging in NSNE tumors. It was helpful for staging, restaging, follow-up after treatment and for the detection of new not previously suspected lesions.
Conclusions: PET with FDG could have a prognostic role and help in patient management, mainly in musculoskeletal and high grade or less differentiated sarcomas. In GIST, it was a good tool for immunotherapy control.
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http://dx.doi.org/10.4067/S0034-98872012000900003 | DOI Listing |
Ultrason Sonochem
November 2022
NanoTheranostics Laboratory, Australian Center for Blood Diseases, Monash University, Melbourne, VIC 3004, Australia. Electronic address:
Nisin, a peptide used as a natural food preservative, is employed in this work for the development of a novel nanocarrier system. Stable and uniform nisin-shelled nanoemulsions (NSNE) with a diameter of 100 ± 20 nm were successfully prepared using 20 kHz flow-through ultrasonication technique. The NSNE showed limited toxicity, high bactericidal activity and high drug loading capacity (EE 65 % w/w).
View Article and Find Full Text PDFRev Med Chil
September 2012
Sección Medicina Nuclear, Departamento de Medicina, Hospital Clínico Universidad de Chile, Chile.
Background: The usefulness of positron emission tomography (PET) with fluorine-deoxyglucose (FDG) in sarcomas and non-sarcoma non-epithelial (NSNE) tumors is not clearly defined.
Aim: To report a Chilean experience with NSNE tumors evaluated using PET with FDG.
Material And Methods: Retrospective review of the database of a PET laboratory.
Exp Oncol
December 2004
Department of Forensic Pathology, Medical School, University of Ioannina, Greece.
Aim: To compare the expression of anti-apoptotic protein bcl-2 and tissue proliferation Ki-67 antigen in tissues of human papillary thyroid carcinoma (PTC) and papillary thyroid microcarcinoma (PTMC).
Methods: Bcl-2 protein expression in PTC and PTMC has been evaluated by immunohistochemical analysis.
Results: Bcl-2 protein was observed in normal thyroid gland in all the cases; in 25% of the cases of papillary carcinomas the immunoreaction was strong and in 75% of the cases--moderate.
Pathol Int
November 1995
First Department of Pathology, Oita Medical University, Japan.
Three hundred and seven lesions of papillary microcarcinoma of the thyroid (PMT), found in 6830 cases of Graves' disease, were reviewed to evaluate the morphological characteristics. The prevalence rate and incidence of multiplicity of PMT in Graves' disease were higher (P < 0.05 and P < 0.
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