AI Article Synopsis
- The study focuses on an Iridium-catalyzed reaction that combines cyclic N-sulfonyl ketimines and 1,3-dienes in a [3 + 2] annulation process.
- This reaction proceeds through the formation of an aryliridium intermediate, utilizing C-H activation, which is a key step in the mechanism.
- The result of the reaction is the production of aminoindane derivatives, which are obtained in high yields and exhibit both high regioselectivity and diastereoselectivity.
Article Abstract
Ir-catalyzed [3 + 2] annulation of cyclic N-sulfonyl ketimines with 1,3-dienes, in which an aryliridium intermediate is formed via C-H activation, gives aminoindane derivatives in high yields with high regio- and diastereoselectivity.
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| http://dx.doi.org/10.1021/ja311968d | DOI Listing |
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