Background: The skin possesses unique biochemical properties that allow it to protect and conform to the body that it covers. Elements constituting the dermis-collagen and elastin-primarily afford these properties.
Objectives: To define these properties and explore their relevance with regard to aging skin and dermatologic surgery.
Materials And Methods: In the first part of this review, the determinants of mechanical properties of the skin will be outlined, through an extensive review of the literature. General physical properties that explain the behavior of skin will be defined, and diseases that manifest the extremes of those properties will be discussed. In the second half of this discussion, the surgical implications of skin biomechanics will be reviewed.
Results: Emphasis will be placed on understanding how dermatologic surgeons may optimally use skin properties to produce the best cosmetic and functional outcomes possible.
Conclusion: Understanding of the biomechanical properties of skin is paramount to obtain the best cosmetic outcomes in dermatologic surgery.
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http://dx.doi.org/10.1111/dsu.12095 | DOI Listing |
Int J Biol Macromol
December 2024
School of Basic Medical Sciences, Guangdong Pharmaceutical University, Guangzhou 510006, China. Electronic address:
The self-assembled peptide RADA16-I (RADARADARADARADA) has been widely used in biomaterials. However, studies on the practical application of self-assembled peptide hydrogels loaded with bioactive peptides are still insufficient. In this study, we successfully prepared the peptide nanofiber gel RGJ by incorporating the bioactive peptides A8SGLP-1 (G) and Jagged-1 (J) into RADA16-I (R) in specific ratios.
View Article and Find Full Text PDFPLoS One
December 2024
Key Laboratory of Animal Genetics, Breeding and Reproduction in the Plateau Mountainous Region, Ministry of Education, Guizhou University, Guiyang, Guizhou Province, China.
Objective: To verify the accuracy of collagen-specific SNP mutation loci of Kele pigs selected by whole genome resequencing, and to excavate collagen-related genes of Kele pigs, so as to lay a foundation for further molecular selection.
Methods: Based on whole genome resequencing, candidate genes related to collagen trait of Kele pig were screened for gene annotation. Through KEGG and GO enrichment analysis of differential genes, we selected four genes that may affect collagen trait of collagen pig, namely COL9A1, COL6A5, COL4A3 and COL4A4.
Eur J Sport Sci
January 2025
Nutrition and Sports Performance Research Group, The Jerzy Kukuczka Academy of Physical Education in Katowice, Katowice, Poland.
This study aimed to investigate the effects of performing either eccentric-only (ECC) or eccentric-concentric (ECC-CON) back squats (BS) with a supramaximal load on countermovement jump (CMJ) performance. Changes in front thigh skin surface temperature and mechanical properties (oscillation frequency and stiffness) of the vastus lateralis were also examined. Fourteen male powerlifters participated in this study (age: 22.
View Article and Find Full Text PDFBr J Community Nurs
January 2025
Freelance medical writer and journalist.
Skin ageing is an inevitable process influenced by both intrinsic and extrinsic factors. Intrinsic aging leads to thinner, drier and less elastic skin with fine wrinkles, while extrinsic factors such as sun exposure, smoking and environmental stresses amplify these changes. Photo-ageing, in particular, causes deep wrinkles, uneven pigmentation and increases the risk of skin cancers.
View Article and Find Full Text PDFJ Cosmet Dermatol
January 2025
Queen's Medical Research Institute, Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
Background: Coenzyme Q10 (CoQ10) is widely recognized for its powerful antioxidant properties, sparking considerable interest in its application within skincare treatments. However, its inherently poor water solubility has posed a major challenge in formulating effective skincare products.
Methods: This research aimed to develop and evaluate a water-soluble CoQ10 serum by forming a complex with hydroxypropyl β-cyclodextrin (HPβCD).
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