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| http://dx.doi.org/10.2337/dc12-2305 | DOI Listing |
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21 century surface UV radiation changes deduced from CMIP6 models: part I-evolution of major influencing factors.
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Institute of Meteorology and Climate Research Atmospheric Trace Gases and Remote Sensing, Karlsruhe Institute of Technology, Karlsruhe, Germany.
For a given solar elevation, the levels of solar ultraviolet radiation at the Earth's surface are determined by the amounts of ozone, aerosols, and clouds, as well as by the reflectivity of the surface. Here, we study the evolution of these factors for three selected decades in the period 1950-2100 using results from simulations with Earth-System models (ESMs) participating in the 6 phase of the Coupled Model Intercomparison Project (CMIP6). The simulations for the future are based on three Shared Socioeconomic Pathways: SSP1-2.
View Article and Find Full Text PDFUnveiling the mechanism of action of a novel natural dual inhibitor of SARS-CoV-2 Mpro and PLpro with molecular dynamics simulations.
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Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, People's Republic of China.
In the twenty-first century, we have witnessed multiple coronavirus pandemics. Despite declining SARS-CoV-2 cases, continued research remains vital. We report the discovery of sydowiol B, a natural product, as a dual inhibitor of SARS-CoV-2 main protease (Mpro) and papain-like protease (PLpro).
View Article and Find Full Text PDFHigh Arctic lakes reveal accelerating ecological shifts linked to twenty-first century warming.
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Department of Geography, Centre for Northern Studies (CEN), & Takuvik International Research Laboratory, Université Laval, Québec, QC, Canada.
The Arctic is among the most rapidly warming regions on Earth, and climate change has triggered widespread alterations to its cryosphere and ecosystems. Among these, high Arctic lakes are highly sensitive to rising temperatures due to the influence of ice cover on multiple limnological processes. Here, we studied the sediments of three lakes on northern Ellesmere Island (82.
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Computing for Sustainability and Social Good (C2SG) Research Group, United International University, Dhaka, Bangladesh.
In the twenty-first century, maritime routes are crucial for geographical and financial reasons in riverine countries. Compared to the available technology abroad, Bangladesh has insufficient monitoring of water vessels to tackle any possible disaster, such as vessel collisions for inland water transportation. One of the frequent outcomes of this architecture is regular capsizing, which sometimes leads to loss of lives.
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