Acute pericarditis is a well-recognized but rare complication of numerous viral infections. We report a case of a 50-year-old woman with novel influenza A (H1N1) infection complicated by pericardial effusion. Resolution of both symptoms and pericardial effusion occurred after a treatment with oseltamivirin and ibuprofen. There were no signs of acute left or right ventricle dysfunction. Pericarditis and pericardial effusion are occasionally associated with influenza A infections. To our knowledge, this is a rare case of pericardial effusion associated with influenza A (H1N1) reported during the current novel influenza A (H1N1) pandemic that responded well to conservative management.

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