AI Article Synopsis
- Hypoxic-ischemic encephalopathy (ENN) affects newborns after 35 weeks of gestation, with an incidence of 1-6 cases per 1000 births, leading to severe neurological issues.
- Before the introduction of cooling treatments, ENN management was primarily symptomatic.
- The article highlights Poland’s first case of ENN treatment using whole body hypothermia, showcasing the potential for improved neurological outcomes through this and selective brain cooling techniques now available in select centers.
Article Abstract
Hypoxic-ischemic encephalopathy (ENN) concerns neonates born after 35 completed weeks of gestation. The incidence rate has been shown to be 1-6/1000 births and can lead to significant permanent neurological damage, cerebral palsy and even death. Until the whole body cooling and selective brain cooling methods have been accepted, the treatment of children with ENN was only symptomatic. The article describes the first case of ENN neonatal treatment with the whole body hypothermia in Poland, which took place at the Department of Neonatology Poznań University of Medical Sciences. Currently both methods--whole body hypothermia and selective brain cooling--offer a chance for a normal neurological development and a better life for children born with ENN. Both methods are accessible in a few centers in Poland.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Novel method to investigate thermal exchange rates in small, terrestrial ectotherms: A proof-of-concept on the gecko Tarentola mauritanica.
PLoS One
December 2024
CIBIO, Research Centre in Biodiversity and Genetic Resources, InBIO, Universidade do Porto, Vila do Conde, Portugal.
Thermoregulating ectotherms may resort to different external heat sources to modulate their body temperature through an array of behavioural and physiological adaptations which modulate heat exchange with the environment and its distribution across the animal's body. Even small-bodied animals are capable of fine control over such rates and the subsequent re-allocation of heat across the body. Such thermal exchanges with the environment usually happen through two non-mutually exclusive modes: heliothermy (radiant heat gain from the sun) or thigmothermy (heat gained or lost via conduction).
View Article and Find Full Text PDFAge-related differences in gene expression and pathway activation following heat stroke.
Physiol Genomics
December 2024
Experimental Medicine Department, King Abdullah International Medical Research Center, King Saud bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Riyadh, 11481, Saudi Arabia.
This study investigates the molecular responses to heat stroke in young and old patients by comparing whole-genome transcriptomes between age groups. We analyzed transcriptomic profiles from patients categorized into two age-defined cohorts: young (mean age = 44.9 ± 6 years) and old (mean age = 66.
View Article and Find Full Text PDFDesign, Characterization, and Evaluation of Textile Systems and Coatings for Sports Use: Applications in the Design of High-Thermal Comfort Wearables.
ACS Omega
December 2024
Department of Biomedical Engineering, Universidad de los Andes, Bogotá 111711, Colombia.
Exposure to high temperatures during indoor and outdoor activities increases the risk of heat-related illness such as cramps, rashes, and heatstroke (HS). Fatal cases of HS are ten times more common than serious cardiac episodes in sporting scenarios, with untreated cases leading to mortality rates as high as 80%. Enhancing thermal comfort can be achieved through heat loss in enclosed spaces and the human body, utilizing heat transfer mechanisms such as radiation, conduction, convection, and evaporation, which do not require initial energy input.
View Article and Find Full Text PDFManual Dexterity in Open-Water Wetsuited Swimmers: A Cohort Crossover Study.
Int J Sports Physiol Perform
December 2024
Department of Anesthesiology and Intensive Care, Akershus University Hospital, Lørenskog, Norway.
Purpose: Laboratory studies have demonstrated that manual dexterity decreases with increasing cold, which may adversely affect performance. Dexterity may be impaired by cooling of the hand, cooling of the lower motor neurons, and cognitive impairment. Wetsuits are commonly used in open-water swimming and are mandated in some situations.
View Article and Find Full Text PDFDoes body cooling facilitated by bedding compared to control condition improve sleep among adults (18-64 years old)? A systematic review and meta-analysis.
J Therm Biol
December 2024
Laboratory of Sport, Expertise and Performance (EA 7370), French National Institute of Sport (INSEP), Paris, France. Electronic address:
Introduction: The relationship between blood distribution, body temperature, and sleep/wakefulness states is still unclear. The aim of the present study is to systematically review the potential beneficial effects of bedding strategies (e.g.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!