This study examined changes in body mass index (BMI), fasting blood sugar (FBS), total cholesterol (TC) and HDL-cholesterol (HDL-C) levels over a 24-year follow-up period in a pediatric cohort. An appropriate starting age for intervention to prevent cardiovascular diseases is still unclear. The subjects were 655 children, aged 10-12. A follow-up survey was conducted when the subjects reached ages 13-15, 16-18, and 35-45, respectively, and height, weight, and blood tests including FBS, TC and HDL-C were examined. Forty (6%) of these subjects participated. BMI at ages 35-45 were significantly higher than those at ages 10-12 (p < 0.0001), 13-15 (p < 0.001), and 16-18 (p < 0.001). TC levels at ages 35-45 were significantly higher than at ages 10-12 (p < 0.0001), 13-15 (p < 0.0001), and 16-18 (p < 0.0001). BMI at the end of the follow-up (ages 35-45) had a significant correlation with BMI at ages 13-15 (R = 0.38, p = 0.041) and 16-18 (R = 0.41, p = 0.049). TC and HDL-C values at the end of the follow-up had a significant correlation with those at ages 10-12 (R = 0.55, p = 0.0004; R = 0.55, p = 0.016), 13-15 (R = 0.35, p = 0.045; R = 0.42, p = 0.015), and 16-18 (R = 0.47, p = 0.019; R = 0.44, p = 0.028). These results may suggest that intervention for children in Japan with cardiovascular risk factors should be initiated in the early years of life.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Is fluoroscopy-free single-use flexible ureteroscopy a feasible treatment for kidney stones with abnormal renal anatomy?
Asian J Urol
October 2024
Urology Department, Menoufia University Hospital, Egypt.
Article Synopsis
- The study evaluated a fluoroscopy-free, single-use flexible ureteroscopy procedure for treating kidney stones, comparing patients with abnormal renal anatomy (Group A) to those with normal anatomy (Group B).
- A total of 120 patients (40 with abnormal anatomy and 80 with normal) were treated, showing no significant differences in operative time, hospital stay, or stone-free rates between the two groups.
- The procedure was mostly completed without fluoroscopy with a high stone-free rate (93%) for stones sized 10-15 mm, indicating that this method is feasible for patients with kidney stones, especially those with abnormal renal anatomy.
Lifetime effects and cost-effectiveness of statin therapy for older people in the United Kingdom: a modelling study.
Heart
October 2024
Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Background: Cardiovascular disease (CVD) risk increases with age. Statins reduce cardiovascular risk but their effects are less certain at older ages. We assessed the long-term effects and cost-effectiveness of statin therapy for older people in the contemporary UK population using a recent meta-analysis of randomised evidence of statin effects in older people and a new validated CVD model.
View Article and Find Full Text PDFAssociation between Methylenetetrahydrofolate Reductase () and 5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase () Polymorphisms in Iraqi Patients with COVID-19.
Iran J Med Sci
July 2024
Ministry of Science and Technology, Baghdad, Iraq.
Background: The methylenetetrahydrofolate reductase () gene is an essential gene in the metabolism of folate-homocysteine. Recently, the level of homocysteine was found to be a significant marker in the follow-up of COVID-19 infection. Thus, this study aimed to detect the effect of genetic polymorphisms for single nucleotide polymorphisms (SNPs) (c.
View Article and Find Full Text PDFThe Benefits of Quitting Smoking at Different Ages.
Am J Prev Med
November 2024
Department of Health Management and Policy, University of Michigan School of Public Health, Ann Arbor, Michigan.
Introduction: Quantifying the impact of smoking on life expectancy and the potential benefits of smoking cessation is crucial for motivating people who smoke to quit. While previous studies have attempted to estimate these effects, they were conducted more than a decade ago and did not include a significant demographic, people over 65 years old who smoke.
Methods: Mortality rates by age and smoking status were calculated using mortality relative risks derived from Cancer Prevention Study II, 2018 National Health Interview Survey smoking prevalence data, 2018 U.
Single-center retrospective study of the diagnostic value of double-balloon enteroscopy in Meckel's diverticulum with bleeding.
World J Gastrointest Surg
April 2024
Yunnan Digestive Endoscopy Clinical Medical Center, Department of Gastroenterology, The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming 650032, Yunnan Province, China.
Background: The study aimed to analyze the characteristic clinical manifestations of patients with intestinal disease Meckel's diverticulum (MD) complicated by digestive tract hemorrhage. Moreover, we aimed to evaluate the value of double-balloon enteroscopy (DBE) in MD diagnosis and the prognosis after laparoscopic diverticula resection.
Aim: To evaluate the value of DBE in the diagnosis and the prognosis after laparoscopic diverticula resection for MD with bleeding.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!