Oral anticoagulants in older adults with atrial fibrillation.

J Thromb Thrombolysis

Division of Cardiology, Duke University Medical Center, Duke Clinical Research Institute, 2400 Pratt Street, Durham, NC, 27705, USA,

Published: November 2013

AI Article Synopsis

  • * There is an increasing demand for safe and effective treatments for AF, particularly for older adults who are at greater risk for complications.
  • * The review discusses the use of oral anticoagulants in treating AF in older patients, emphasizing practical concerns such as how these drugs are processed in the body, interactions with other medications, existing health issues, and the financial aspects related to insurance and healthcare costs.

Article Abstract

Atrial fibrillation (AF) is the most common arrhythmia in adults and contributes directly to adverse clinical events, ranging from ischemic stroke to heart failure and cardiovascular death. Because the incidence of AF and its attendant complications increase with age, there is a strong and growing need to develop safe, effective and widely available therapies. The following review summarizes the use of oral anticoagulants in older adults with AF, focusing on practical topics such as drug metabolism, drug-drug interactions, co-morbidities and cost considerations in a complex payer environment.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037576PMC
http://dx.doi.org/10.1007/s11239-013-0869-0DOI Listing

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