(Me)FGC(Bz)DEVD was radiolabeled with technetium-99m in high yield. This tracer was preferentially accumulated in apoptotic cells in the in vitro studies. Tumor uptake occurred in vivo after cisplatin injection due to the apoptosis induction, which not observed in the untreated tumors. Therefore, (99m)Tc-(Me)FGCDEVD is a potential tracer for apoptosis detection.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.bmcl.2012.12.088 | DOI Listing |
Publication Analysis
Top Keywords
potential tracer
8
tracer apoptosis
8
apoptosis detection
8
⁹⁹mtc-mefgcdevd potential
4
detection mefgcbzdevd
4
mefgcbzdevd radiolabeled
4
radiolabeled technetium-99m
4
technetium-99m high
4
high yield
4
yield tracer
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!