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A hybrid PDMS-Parylene subdural multi-electrode array. | LitMetric

A hybrid PDMS-Parylene subdural multi-electrode array.

Biomed Microdevices

School of Electrical and Computer Engineering, Purdue University, West Lafayette, IN 47907, USA.

Published: June 2013

AI Article Synopsis

  • A cost-effective and simple method was developed for creating a flexible multi-electrode array suitable for recording neural activity subdurally, using a combination of PDMS and Parylene materials.
  • The fabricated 16-site electrode array was tested for its mechanical and electrical performance while being flexed around various shapes, such as a cylindrical tube and a sphere, without losing its recording capability.
  • Successful recordings of acoustically evoked neural activity from the rat auditory cortex were achieved, demonstrating the array's effectiveness in in vivo applications.

Article Abstract

In this paper, we report on a cost effective and simple method for fabricating a flexible multi-electrode array for subdural neural recording. The electrode was fabricated using a PDMS-Parylene bilayer to combine the major advantages of both materials. Mechanical and electrical characterizations were performed to confirm functionality of a 16-site electrode array under various flexed/bent conditions. The electrode array was helically wound around a 3 mm diameter cylindrical tube and laid over a 2 cm diameter sphere while maintaining its recording capability. Experimental results showed impedance values between 300 kΩ and 600 kΩ at 1 kHz for 90 μm diameter gold recording sites. Acoustically evoked neural activity was successfully recorded from rat auditory cortex, confirming in vivo functionality.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651747PMC
http://dx.doi.org/10.1007/s10544-013-9743-2DOI Listing

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