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A clinical analysis and literature review of eleven cases with primary pulmonary angiosarcoma.
BMC Cancer
December 2024
National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510000, China.
Objective: The aim of this study is to explore the clinicopathological features, radiographic manifestations, treatment options, and prognosis of primary pulmonary angiosarcoma (PPAS).
Method: We summarized and analyzed the clinical data of 11 patients with primary pulmonary angiosarcoma treated at the First Affiliated Hospital of Guangzhou Medical University between January 2018 and January 2024. A retrospective analysis was conducted in conjunction with a review of the relevant literature.
Case report: A rare case of renal epithelioid angiosarcoma.
Front Oncol
December 2024
Department of Urology and Andrology, The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, China.
Primary renal epithelioid angiosarcoma (EAS) is extremely rare and carries a poor prognosis. Herein, we present a case of renal EAS in an 81-year-old male patient who complained of hematuria for 1 year. A computerized tomography (CT) scan revealed an occupying lesion at the upper pole of the left kidney, with scattered calcifications, along with retroperitoneal lymph node metastasis and possible lung metastasis.
View Article and Find Full Text PDFUnveiling a rare haemorrhagic malignant pleural effusion: The role of medical thoracoscopy in diagnosing primary pleural angiosarcoma.
Respirol Case Rep
November 2024
Division of Respiratory Medicine, Department of Internal Medicine Melaka Hospital Melaka Malaysia.
Article Synopsis
- Primary pleural angiosarcoma (PPA) is a rare and difficult-to-diagnose tumor often confused with other cancers like mesothelioma and lung cancer due to similar symptoms and imaging results.
- A 52-year-old woman experienced severe shortness of breath and chest pain, with imaging revealing a large bleeding pleural effusion and medical thoracoscopy identifying abnormal pleura with nodular lesions.
- Diagnosis was confirmed through histopathology with specific tumor markers, but unfortunately, the patient developed an infection and died before receiving treatment, highlighting the challenges in diagnosing PPA.
Mediastinal angiosarcoma mimicking constrictive pericarditis and aortic dissection: a case report.
Gen Thorac Cardiovasc Surg Cases
February 2024
Department of Cardiovascular Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
Article Synopsis
- * A case involving a 49-year-old man revealed that initial diagnoses suggested other conditions like constrictive pericarditis, but surgery ultimately confirmed the presence of a malignant tumor after only a pericardiectomy was performed.
- * The study highlights that mediastinal angiosarcoma can present with diverse symptoms resembling other diseases, and suggests that high hyaluronic acid concentration in pleural fluid could be a potential diagnostic marker.
Multifocal vascular neoplasm with an EWSR1::NFATC2 gene fusion and progression to epithelioid angiosarcoma - a case report.
Virchows Arch
December 2024
Institute of Pathology, Faculty of Medicine, University of Ljubljana, Korytkova 2, 1000, Ljubljana, Slovenia.
There is an emerging group of distinct vascular neoplasms with NFATC1/2 fusions, involving bones and soft tissues and often displaying focal epithelioid morphology, variable atypia of endothelial cells, predominantly vasoformative and in some cases focal solid growth. Although they may show aggressive local growth and may recur locally, malignant behaviour has not been documented. We present a case of a 35-year-old woman with multiple vascular neoplasms with a EWSR1::NFATC2 fusion involving the lungs, multiple bones (vertebra, femurs, tibia, pelvis) and probably the liver.
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