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Possible aspects of using cultured stem cell of laboratory primates in experimental medicine. | LitMetric
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Possible aspects of using cultured stem cell of laboratory primates in experimental medicine.

V Z Agrba V A Porkhanov A G Konoplyannikov S Sh Kal'sina D D Karal-ogly I E Ignatova T E Gvozdik A A Agumava A V Leontiuk B A Lapin

Bull Exp Biol Med

Research Institute of Medical Primatology, Russian Academy of Medical Sciences, Sochi, Russia.

Published: November 2012

We describe the methods of isolation and culturing of mesenchymal stem cells from 3 monkey species Macaca mulatta, Papio hamadryas, and Macaca fascicularis. Flow cytofluorometry showed that the cells do not express CD34, CD45, and HLA-DR, but most of them (78-98%) express CD90 marker. The cardioprotective effects of cultured mesenchymal stem cells in cardiomyopathy induced by administration of antitumor anthracycline drugs (doxorubicin).

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http://dx.doi.org/10.1007/s10517-012-1893-3DOI Listing

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