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Intestinal histoplasmosis with granulomatous colonic and mesenteric lymphadenitis due to Histoplasma mississippiense infection in an American Mammoth Jackstock donkey (Equus asinus).
J Comp Pathol
January 2025
Department of Pathobiology and Population Medicine, Mississippi State University, 240 Wise Center Drive, Mississippi State, Mississippi 39762, USA.
Histoplasmosis is a rarely reported clinical disease of equids in North America and is historically attributed to Histoplasma capsulatum var. capsulatum. This report details a case of intestinal histoplasmosis with lymphadenitis in an American Mammoth Jackstock donkey from Mississippi.
View Article and Find Full Text PDFJejunal Perforation Due to Histoplasmosis Regarding a Case.
Surg Infect (Larchmt)
November 2024
Department of Surgery, Central Military Hospital, Bogotá, Colombia.
Histoplasmosis is an increasing infection that mainly affects immunocompromised individuals such as patients with HIV/AIDS, with the disseminated form, especially gastrointestinal, being common in this population. The clinical presentation ranges from asymptomatic to symptoms that mimic other abdominal diseases. Jejunal perforation due to histoplasmosis, although rare, has been reported in a few cases, typically in men living with HIV in their fourth decade of life.
View Article and Find Full Text PDFA Rare Case of Disseminated Histoplasmosis Involving the Colon and Brain.
Cureus
April 2024
Infectious Disease, Baylor Scott & White Medical Center, Mckinney, USA.
, the causative organism for histoplasmosis, is a dimorphic fungus seen abundantly along the river valleys of Ohio and Mississippi in the United States of America as well as in other parts of the world. The infection is primarily acquired by inhaling the fungal spores which are often found in bird and bat droppings. Histoplasmosis can have a wide range of presentations ranging from no symptoms to mild flu-like or life-threatening consequences if severe.
View Article and Find Full Text PDFGastrointestinal bleeding due to disseminated histoplasmosis in a patient under anti-TNF treatment.
Rev Esp Enferm Dig
April 2024
Aparato Digestivo, Hospital Universitario La Paz.
A 62-year-old woman, originally from Peru, with rheumatoid arthritis under treatment with anti-tumor necrosis factor (anti-TNF) therapy, was admitted due to constitutional syndrome and suspicion of neoplasia. Computed tomography (CT) scan revealed involvement of three segments of the colon, ascites, and likely peritoneal implants. Ascitic fluid analysis showed elevated adenosine deaminase (ADA) levels and lymphocytosis.
View Article and Find Full Text PDFGastrointestinal histoplasmosis with small intestinal perforation: 20-year experience.
Updates Surg
June 2024
Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, MN, USA.
Postmortem studies show gastrointestinal tract involvement in as many as 70% of patients affected by disseminated histoplasmosis. Although gastrointestinal involvement is common in disseminated disease, the presentation of small intestinal perforation is exceedingly rare with few reported cases in the literature. Herein we present our institutional case series.
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