A new tripodal receptor and a novel dyed mesoporous material are presented. The presence of thioureas conjugated with azobenzene chromophores enables the selective colorimetric detection of mercury(II) cations in THF through a remarkable colour change from yellow to deep purple.
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http://dx.doi.org/10.1039/c2dt32243a | DOI Listing |
ACS Biomater Sci Eng
January 2025
State Key Laboratory of New Textile Materials and Advanced Processing Technologies, Wuhan Textile University, Wuhan 430200, China.
In most studies, the penetration of nanoparticles into tumors was mainly dependent on the enhanced permeability and retention (ERP) effect. However, the penetration of nanoparticles would be limited by tumor-dense structure, immune system, and other factors. To solve these problems, macrophages with active tropism to tumor tissues, loaded nanoparticles with photothermal therapy, and chemotherapy were designed.
View Article and Find Full Text PDFNanomaterials (Basel)
January 2025
Yunnan Key Laboratory of Modern Separation Analysis and Substance Transformation, College of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming 650500, China.
We successfully synthesize monodisperse sulfhydryl-modified mesoporous organosilica nanospheres (MONs-SH) via one-step hydrolytic condensation, where cetyltrimethylammonium chloride and dodecyl sulfobetaine are employed as dual-template agents with (3-mercaptopropyl)triethoxysilane and 1,2-bis(triethoxysilyl)ethane as the precursors and concentrated ammonia as the alkaline catalyst. The prepared MONs-SHs deliver a large specific surface area (729.15 m g), excellent monodispersity, and homogeneous particle size.
View Article and Find Full Text PDFJ Pharm Anal
December 2024
Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang, Liaoning Province 110016, China.
Particle size and surface properties are crucial for lymphatic drainage (LN), dendritic cell (DC) uptake, DC maturation, and antigen cross-presentation induced by nanovaccine injection, which lead to an effective cell-mediated immune response. However, the manner in which the particle size and surface properties of vaccine carriers such as mesoporous silica nanoparticles (MSNs) affect this immune response is unknown. We prepared 50, 100, and 200 nm of MSNs that adsorbed ovalbumin antigen (OVA) while modifying -glucan to enhance immunogenicity.
View Article and Find Full Text PDFCarbohydr Polym
March 2025
Key Laboratory of Biotechnology and Bioresources Utilization of Ministry of Education, College of Life Science, Dalian Minzu University, Dalian 116600, PR China; Department of Bioengineering, College of Life Science, Dalian Minzu University, Dalian 116600, PR China. Electronic address:
The limited membrane permeability and bacterial resistance pose significant challenges in the management of intracellular drug-resistant bacterial infections. To overcome this issue, we developed a bacterial-targeted drug delivery system based on quaternary ammonium chitosan-modified mesoporous silica nanoparticles (MSN-NH-CFP@HACC) for the treatment of intracellular Methicillin-resistant Staphylococcus aureus (MRSA) infections. This system utilizes amino-functionalized mesoporous silica nanoparticles to efficiently load cefoperazone (CFP), and the nanoparticles' surface is coated with 2-hydroxypropyltrimethyl ammonium chloride chitosan (HACC) to target bacteria and enhance macrophage uptake.
View Article and Find Full Text PDFAdv Mater
January 2025
Key Lab of Artificial Micro- and Nano-Structures of Ministry of Education of China, School of Physics and Technology, Wuhan University, Wuhan, 430072, China.
Porous lead iodide (PbI) film is crucial for the complete reaction between PbI and ammonium salts in sequential-deposition technology so as to achieve high crystallinity perovskite film. Herein, it is found that the tensile stress in tin (IV) oxide (SnO) electron transport layer (ETL) is a key factor influencing the morphology and crystallization of PbI films. Focusing on this, lithium trifluoromethanesulfonate (LiOTf) is used as an interfacial modifier in the SnO/PbI interface to decrease the tensile stress to reduce the necessary critical Gibbs free energy for PbI nuclei formation.
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