Background: Depression and psychosis are severe diseases with onset in adolescence.

Aims: The aim of this study was to investigate the association between an at-risk status of psychosis and depression symptoms in adolescents.

Method: The data were collected by an early intervention team in Finland. The PROD screen was used to assess the risk of psychosis, and Beck Depression Inventory-II was used as a measurement to assess the level of depression symptoms. Of 203 help-seeking respondents, 66 were classified as at-risk for psychosis, and 137 respondents were other help-seekers. The mean age of the subjects was 15.3 years.

Results: Subjects at-risk had significantly poorer scores in total scores for depression (p  <  0.001), and in an item-by-item analysis, the subjects at-risk had poorer scores for sadness (p  <  0.001), past failure (p  =  0.001), suicidal thoughts (p  <  0.001), crying (p  =  0.002), agitation (p  =  0.001), loss of energy (p  =  0.002) and concentration difficulty (p  <  0.001). In a logistic regression analysis of items that differed by risk status for psychosis, item of concentration difficulty (p  =  0.038) explained the at-risk status after adjustment for sex.

Conclusions: The present results suggest that subjects that are at-risk for psychosis have more depression symptoms than other help-seekers. This should be considered in the psychiatric care of adolescents.

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http://dx.doi.org/10.3109/09638237.2012.734654DOI Listing

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