[Optimization of the extraction process for qingrejiedu oral liquid with synthesizing multiple guidelines grading method].

Objective: To optimize the extraction process for Qingrejiedu oral liquid with synthesizing multiple guidelines grading method.

Methods: Used the extraction rate of baicalin and geniposide comprehensive contribution rate variance as index, extraction time and added water were as factors, central composite design was used for optimization of extraction process, and forecasting analysis parameters.

Results: The optimal extraction process was as follows: extraction time 139 min, added water 13 times, grading index was 0.768.

Conclusion: Synthesizing multiple guidelines grading method is ideal for multi-component extraction experiment design, its easy application, the forecast is good and so on.