Anaphylaxis is a rare condition in pregnancy. Drugs are the aetiological agents most often implicated. Maternal anaphylaxis can lead to significant fetal morbidity and even mortality if uterine perfusion and maternal oxygenation are compromised. Significant risk of neonatal neurological damage or death can occur even when the maternal clinical outcome is favourable. The authors present the case of a newborn, born at gestational age of 29 weeks, who died at 11 days of life with hypoxic-ischaemic cerebral injuries as a consequence of maternal anaphylaxis following the administration of amoxicillin in the community setting.
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http://dx.doi.org/10.1136/bcr-2012-007055 | DOI Listing |
Zhonghua Yu Fang Yi Xue Za Zhi
December 2024
Department of Anaphylaxis, Maternal and Child Health Hospital of Gansu Province, Lanzhou730050, China.
Cow's milk protein allergy is the most common food allergy in infants and young children, and its prevalence has been increasing in recent years. The use of appropriate diagnostic methods is essential for the management of patients. Oral food challenges are not yet widely used in clinical practice, and new and more effective methods are still being sought, including component resolved diagnosis.
View Article and Find Full Text PDFCochrane Database Syst Rev
December 2024
Cochrane Denmark and Centre for Evidence-Based Medicine Odense (CEBMO), University of Southern Denmark, Odense, Denmark.
Rationale: Postpartum iron deficiency anaemia is caused by antenatal iron deficiency or excessive blood loss at delivery and might affect up to 50% of labouring women in low- and middle-income countries. Effective and safe treatment during early motherhood is important for maternal well-being and newborn care. Treatment options include oral iron supplementation, intravenous iron, erythropoietin, and red blood cell transfusion.
View Article and Find Full Text PDFPediatr Res
November 2024
Department of Pediatric Allergy and Immunology, University of Health Sciences Ankara City Hospital, Ankara, Turkey.
Background: Diagnosing anaphylaxis in children within the first 2 years of life can be difficult due to the often confusing and nonspecific signs and symptoms.
Objective: This study focuses on the phenotype of anaphylaxis in children within the first 2 years of life and aims to increase awareness of anaphylaxis in this age group.
Methods: The study included children between 0 and 2 years who were diagnosed as having anaphylaxis by pediatric allergists in 11 tertiary hospitals.
Phytomedicine
December 2024
State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China; Foshan Maternal and Child Health Research Institute, Foshan Women and Children's Hospital Affiliated to Southern Medical University, Foshan, China. Electronic address:
Background: Food allergies, particularly peanut (PN) allergies, are a growing concern, with fatal anaphylaxis incidents often reported. While palforzia is the sole FDA-approved drug for managing PN allergies, it is not universally effective.
Purpose: This study aimed to investigate the potential of Gynostemma pentaphyllum saponins (GpS) as a novel therapeutic agent for PN allergy through modulation of gut microbiota, addressing the limitations of current treatments.
Nutrients
November 2024
Section of Pediatric Allergy and Immunology, Children's Hospital Colorado, University of Colorado, Boulder, CO 80309, USA.
Background/objectives: An adapted version of an online pictorial food frequency questionnaire (FFQ), VioScreen-Allergy, assesses total dietary intake and intake of allergens and foods in the maternal diet index (MDI), linked to offspring allergy. This study assessed intermethod reliability, test-retest reliability, and external validity of the VioScreen-Allergy.
Methods: Females of childbearing age were recruited at Denver Health and Children's Hospital, Colorado, USA, and were asked to complete four 24 h recalls and two VioScreen-Allergy FFQs over the course of a month.
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