Previous efforts to diagnose the cause of this patient's rash had been unsuccessful. A biopsy confirmed our suspicions.
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Article Synopsis
- The article presents a clinical case of a young patient with HPV-associated penile intraepithelial neoplasia (PIN), specifically the erythematous form of bowenoid papulosis.
- It highlights the issues of delayed diagnosis due to improper diagnostic approaches and a lack of awareness among doctors about cancer-related diseases.
- The piece emphasizes the significance of early detection in preventing progression to more severe conditions like squamous cell penile carcinoma, detailing the different subtypes of PIN and their varying risks of leading to cancer.
Squamous Cell Carcinoma In Situ-The Importance of Early Diagnosis in Bowen Disease, Vulvar Intraepithelial Neoplasia, Penile Intraepithelial Neoplasia, and Erythroplasia of Queyrat.
Diagnostics (Basel)
August 2024
Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Article Synopsis
- - Cutaneous squamous cell carcinoma (cSCC) is a common skin cancer, with early recognition being crucial as delayed diagnosis can lead to more aggressive forms and surgical complications.
- - Bowen's disease (BD) is an early stage of cSCC that shows specific skin features, but histopathology is essential for accurate diagnosis and treatment planning.
- - Diagnosing precancerous conditions like vulvar and penile intraepithelial neoplasia (VIN and PeIN) can be complex, often requiring multiple biopsies and utilizing techniques like immunostaining and HPV testing to guide treatment options.
Fixed Drug Eruption on the Penis Due to Trimethoprim-Sulfamethoxazole: A Case Report.
Cureus
July 2024
Department of Health, Fundación Jesús Carpintero, La Libertad, ECU.
Article Synopsis
- A fixed drug eruption (FDE) is a skin condition caused by medication, often unnoticed, where patients develop red, itchy lesions in areas like the face, torso, and genitals after taking a drug.* -
- The condition can be misdiagnosed as other skin issues, making it challenging for primary care physicians if they don’t suspect it.* -
- Treatment involves stopping the offending drug and applying topical corticosteroids, which can resolve symptoms and prevent future reactions, exemplified by a case of a 26-year-old man who reacted to trimethoprim-sulfamethoxazole.*
Clinical Characteristics and Pathogen Spectrum of Male Genital Fungal Infections in Nanchang Area, South China.
Mycopathologia
April 2024
Dermatology Hospital of Jiangxi Province, Jiangxi Provincial Clinical Research Center for Skin Diseases, Candidate Branch of National Clinical Research Center for Skin Diseases, 388 Yingbinbei Road, Nanchang, 330001, China.
Article Synopsis
- Cutaneous fungal infections in male genitalia are uncommon and often present with atypical symptoms, with limited large-scale data available.
- A study examined 79 male patients, revealing that T. rubrum was the most common fungus, affecting 67.6% of patients, followed by C. albicans in 28.4%.
- Key predisposing factors included the presence of other fungal infections, use of corticosteroids, and high moisture levels, highlighting the importance of timely examination and treatment for these infections.
Extramammary Paget's Disease of the Penis and Scrotum.
Indian J Surg Oncol
March 2024
Pathology, PathKind Diagnostics, New Delhi, India.
Extramammary Paget's disease (EMPD) is an adenocarcinoma arising from the skin or skin appendages which is sometimes associated with an underlying malignancy. EMPD is most commonly seen in the vulva, followed by perianal region, and the male genitalia. In most cases, patient presents with eczematous lesion persisting for long duration.
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