Pd(II)-catalyzed enantioselective C-H activation of phenylacetic acids followed by an intramolecular C-O bond formation afforded chiral benzofuranones. This reaction provides the first example of enantioselecctive C-H functionalizations through Pd(II)/Pd(IV) redox catalysis.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578945PMC
http://dx.doi.org/10.1021/ja311259xDOI Listing

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