Synthesis of 3-alkyl- or 3-allenyl-2-amidobenzofurans via electrophilic cyclization of o-anisole-substituted ynamides with carbocations.

Org Lett

Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education, Hangzhou Normal University, Wenyi Road 222, Hangzhou 310012, People's Republic of China.

Published: January 2013

A facile carbocation-induced electrophilic cyclization reaction has been developed for the synthesis of 3-alkyl- or 3-allenyl-2-amidobenzofurans from o-anisole-substituted ynamides and diarylmethanol or 1,1-diarylprop-2-yn-1-ol.

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Source
http://dx.doi.org/10.1021/ol303474aDOI Listing

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