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Follow-up of inguinal hernia repairs using a modified Kugel mesh without the optional onlay mesh for more than 10 years.
J Formos Med Assoc
November 2024
Division of General Practice, Department of Medical Education, Changhua Christian Hospital, Changhua, Taiwan.
Purpose: In this 10-year follow-up study, we evaluated the long-term postoperative results of single-layer modified Kugel (MK) herniorrhaphy without an onlay mesh.
Methods: Patients who underwent anterior modified Kugel herniorrhaphy without an onlay mesh between May 1, 2009, and June 31, 2012, were included in this study. The criterion for onlay mesh omission was that the posterior inguinal hernia defect did not exceed the memory recoil ring of the MK mesh.
Longer Multimorbidity Intervals Are Associated With Lower Mortality in Diabetes: A Whole-Population Nested Case-Control Study.
J Prim Care Community Health
October 2024
The University of Hong Kong, Pok Fu Lam, Hong Kong SAR.
Background: Approximately two-thirds of diabetes patients develop multimorbidity, which is associated with increased mortality. We aimed to examine whether, and to what extent, the time interval between pre-existing diabetes and a second chronic disease may be associated with the risk of mortality.
Methods: We carried out a territory-wide nested case-control study using incidence density sampling, utilizing electronic health records from Hong Kong's public healthcare facilities.
Use of fluoroquinolones and the risk of aortic and mitral regurgitation: A nationwide case-crossover study.
PLoS One
July 2024
Department of Surgery, Division of Thoracic and Cardiovascular Surgery, Chang Gung Memorial Hospital, Linkou Medical Center, Chang Gung University, Taoyuan City, Taiwan.
Background: Recently, there have been conflicting results reporting an increased risk of AR or MR associated with oral fluoroquinolones (FQs).This study investigated whether the use of FQs increases the risk of mitral regurgitation (MR) or aortic regurgitation (AR).
Methods: A retrospective cohort study was conducted by using the Taiwan National Health Insurance research database.
Risk of respiratory diseases among hospitalized patients with hidradenitis suppurativa.
Int J Dermatol
November 2024
Division of Dermatology, Department of Medicine, University of Toronto, Toronto, Canada.
Background: Hidradenitis suppurativa (HS) is a systemic disorder associated with various metabolic and inflammatory comorbidities. Although HS shares risk factors and pathogenic pathways with various respiratory conditions, few studies have explored the relationship between HS and respiratory disease.
Methods: This is a cross-sectional, case-control, population-based study that examined the United States National Inpatient Sample database from January 1, 2002, to December 31, 2012.
Effect of baseline oestradiol serum concentration on the efficacy of anastrozole for preventing breast cancer in postmenopausal women at high risk: a case-control study of the IBIS-II prevention trial.
Lancet Oncol
January 2024
Institute of Cancer Research, Royal Marsden Hospital, London, UK.
Background: An increased risk of breast cancer is associated with high serum concentrations of oestradiol and testosterone in postmenopausal women, but little is known about how these hormones affect response to endocrine therapy for breast cancer prevention or treatment. We aimed to assess the effects of serum oestradiol and testosterone concentrations on the efficacy of the aromatase inhibitor anastrozole for the prevention of breast cancer in postmenopausal women at high risk.
Methods: In this case-control study we used data from the IBIS-II prevention trial, a randomised, controlled, double-blind trial in postmenopausal women aged 40-70 years at high risk of breast cancer, conducted in 153 breast cancer treatment centres across 18 countries.
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