A new fine needle aspiration biopsy technique (Vacu-Cut, 19.5 G) was compared to the 17 G Menghini needle in 20 consecutive patients scheduled for routine percutaneous liver biopsy (10 at random with each needle). The Menghini system was superior in producing sufficient material for histological assessment with 90% success on first pass biopsy (100% with 12 passes in 11 patients) as compared to 60% with the Vacu-Cut needle (90% with 16 passes in 10 patients). The latter was easier to use. Ability to reach a histological diagnosis was 100% with both needles. No major complications occurred: only one Vacu-Cut patient (10%) developed pain at the puncture site as compared to seven patients (65%) in the Menghini group, irrespective of number of passes. The ease of use and lower incidence of pain may favour the Vacu-Cut needle in selected ill patients.
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