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Cerebrovascular risk in rheumatoid arthritis patients: insights from carotid artery atherosclerosis in the Paracelsus 10,000 study.
Rheumatol Int
January 2025
Department of Internal Medicine, General Hospital Oberndorf, Teaching Hospital of the Paracelsus Medical University, Salzburg, Austria.
Rheumatoid arthritis (RA) is a chronic autoimmune disease marked by systemic inflammation. While RA primarily affects the joints, its systemic effects may lead to an increased cerebro- and cardiovascular risk. Atherosclerosis of the carotid arteries is a significant risk factor for cerebrovascular events and serves as a surrogate marker for cardiovascular risk.
View Article and Find Full Text PDFPredictive value of plasma sB7-H3 and YKL-40 in pediatric refractory Mycoplasma pneumoniae pneumonia.
Open Med (Wars)
January 2025
Department of Laboratory Medicine, Changzhou Children's Hospital of Nantong University, No. 958, Zhongwu Avenue, Diaozhuang Street, Tianning District, Changzhou, Jiangsu, 213003, China.
Objective: This study investigated the clinical significance of plasma sB7-H3 and YKL-40 levels in children with refractory Mycoplasma pneumoniae pneumonia (RMPP).
Methods: A total of 182 RMPP patients (103 general Mycoplasma pneumoniae patients and 79 RMPP patients) were included. sB7-H3, YKL-40, and other inflammatory factors were measured.
Correlation of ACE gene polymorphisms and platelet parameters with morning peak blood pressure in hypertensive patients.
Am J Transl Res
December 2024
Department of Cardiology, Wujin Hospital Affiliated with Jiangsu University Changzhou 213004, Jiangsu, China.
Objective: To analyze the relationship between platelet parameters, morning peak blood pressure (MPBP) in hypertensive patients, and angiotensin-converting enzyme (ACE) gene polymorphisms.
Methods: This study included 245 primary hypertensive patients treated between February 2019 and February 2022, who were divided into two groups based on MPBP status: 144 patients with MPBP and 101 without MPBP. Baseline data and early morning fasting blood samples from the antecubital vein were collected.
Effects of high-sensitivity C-reactive protein and left ventricular hypertrophy on cognitive function in hemodialysis patients.
Ren Fail
December 2025
Department of Nephrology, the Affiliated Changzhou Second People's Hospital with Nanjing Medical University, Changzhou, China.
Objectives: To examine the effects of high-sensitivity C-reactive protein (hs-CRP) and left ventricular hypertrophy (LVH) on the cognitive function of hemodialysis (HD) patients, and to explore the relationship between hs-CRP, LVH, and cognitive impairment (CI).
Methods: A cross-sectional study was conducted on 232 HD patients. Besides, general clinical data were gathered, and patients' cognitive functions were assessed using the Beijing version of the Montreal Cognitive Assessment (MoCA-BJ).
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