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At present, it is not well understood how changes in vocal fold biomechanics correspond to changes in voice quality. Understanding such cross-domain links from physiology to acoustics to perception in the "speech chain" is of both theoretical and clinical importance. This study investigates links between changes in body layer stiffness, which is regulated primarily by the thyroarytenoid muscle, and the consequent changes in acoustics and voice quality under left-right symmetric and asymmetric stiffness conditions. Voice samples were generated using three series of two-layer physical vocal fold models, which differed only in body stiffness. Differences in perceived voice quality in each series were then measured in a "sort and rate" listening experiment. The results showed that increasing body stiffness better maintained vocal fold adductory position, thereby exciting more high-order harmonics, differences that listeners readily perceived. Changes to the degree of left-right stiffness mismatch and the resulting left-right vibratory asymmetry did not produce perceptually significant differences in quality unless the stiffness mismatch was large enough to cause a change in vibratory mode. This suggests that a vibration pattern with left-right asymmetry does not necessarily result in a salient deviation in voice quality, and thus may not always be of clinical significance.
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http://dx.doi.org/10.1121/1.4770235 | DOI Listing |
Heliyon
December 2024
Department of Industrial and Data Engineering, Hongik University, Seoul, South Korea.
Introduction: Laryngeal cancer diagnosis relies on specialist examinations, but non-invasive methods using voice data are emerging with artificial intelligence (AI) advancements. Mel Frequency Cepstral Coefficients (MFCCs) are widely used for voice analysis, but Octave Frequency Spectrum Energy (OFSE) may offer better accuracy in detecting subtle voice changes.
Problem Statement: Accurate early diagnosis of laryngeal cancer through voice data is challenging with current methods like MFCC.
J Acoust Soc Am
December 2024
Department of Otorhinolaryngology and Head & Neck Surgery, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan.
The fundamental frequency (fo) is pivotal for quantifying vocal-fold characteristics. However, the accuracy of fo estimation in hoarse voices is notably low, and no definitive algorithm for fo estimation has been previously established. In this study, we introduce an algorithm named, "Spectral-based fo Estimator Emphasized by Domination and Sequence (SFEEDS)," which enhances the spectrum method and conducted comparative analyses with conventional estimation methods.
View Article and Find Full Text PDFJ Voice
December 2024
Department of Duquesne-China Health Institute, John G. Rangos Sr. School of Health Sciences, Duquesne University, Pittsburgh, PA; Speech Science Laboratory, Faculty of Education, The University of Hong Kong, Hong Kong SAR, China.
J Voice
December 2024
Indiana University School of Medicine (IUSM), Indianapolis, Indiana; IUSM Department of Otolaryngology-Head and Neck Surgery, Indianapolis, Indiana; Purdue University Department of Speech, Language, and Hearing Sciences, West Lafayette, Indiana. Electronic address:
Objectives/hypothesis: Given the complex pathology underlying unilateral vocal fold paralysis (UVFP), there has been limited systematic exploration of curative treatments in humans. Central to the investigation of experimental therapies includes establishing a reliable and analogous large animal model. The study goal was to create a standardized porcine model of UVFP by establishing characteristic pathophysiology and functional outcomes.
View Article and Find Full Text PDFFront Cell Dev Biol
December 2024
Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Approaches to regenerate vocal fold in glottic insufficiency remains to be a focus for exploration. This is attributed to the applications of cells or biological molecules alone result in fast degradation and inadequate for regeneration. Development of an injectable hydrogel for glottic insufficiency is challenging, as it needs to be non-cytotoxic, elastic yet possess good strength and easy to fabricate.
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