[Iodine and thyroid gland with or without nuclear catastrophe].

Med Pregl

Klinicki centar Vojvodine, Novi Sad, Klinika za endokrinologiju, dijabetes i bolesti metabolizma, Medicinski fakultet Novi Sad.

Published: January 2013

AI Article Synopsis

  • Iodine is a crucial trace element necessary for the production of thyroid hormones T3 and T4, with iodine deficiency leading to serious health issues like hypothyroidism, cognitive impairments, and goiter.
  • Excessive iodine intake can also cause autoimmune thyroid disorders, demonstrating the importance of balanced iodine levels for thyroid health.
  • The paper discusses the health risks associated with iodine, particularly in the context of nuclear disasters, where exposure to radioactive iodine can significantly increase thyroid cancer rates, especially in children, and highlights the need for preventive measures recommended by the WHO.

Article Abstract

Iodine, as a trace element, is a necessary and limiting substrate for thyroid gland hormone synthesis. It is an essential element that enables the thyroid gland to produce thyroid hormones thyroxine (T4) and triiodothyronine (T3). Synthesis of Thyroid Hormones and Iodine Metabolism. Three iodine molecules are added to make triiodothyronine, and four for thyroxine - the two key hormones produced by the thyroid gland. Iodine deficiency The proper daily amount of iodine is required for optimal thyroid function. Iodine deficiency can cause hypothyroidism, developmental brain disorders and goiter. Iodine deficiency is the single most common cause of preventable mental retardation and brain damage in the world. It also decreases child survival, causes goiters, and impairs growth and development. Iodine deficiency disorders in pregnant women cause miscarriages, stillbirths, and other complications. Children with iodine deficiency disorders can grow up stunted, apathetic, mentally retarded, and incapable of normal movements, speech or hearing. Excessive Iodine Intake. Excessive iodine intake, which can trigger a utoimmune thyroid disease and dysfunction. is on the other side. Iodine use in Case of Nuclear Catastrophe. In addition to other severe consuquences of radioactivity, high amount of radioactive iodine causes significant increase in incidence of thyroid gland carcinoma after some of the nuclear catastrophes (Hiroshima, Nagasaki, Chernobyl, Fukushima). The incidence of thyroid carcinoma was increased mostly in children. This paper was aimed at clarifying some of the possibilities of prevention according to the recommendations given by the World Health Organization.

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http://dx.doi.org/10.2298/mpns1212489tDOI Listing

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