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An illusion of hormesis in the Ames test: statistical significance is not equivalent to biological significance.
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View Article and Find Full Text PDFResveratrol commonly displays hormesis: occurrence and biomedical significance.
Hum Exp Toxicol
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Department of Public Health, Environmental Health Sciences, University of Massachusetts, Amherst, MA 01003, USA.
Resveratrol induces hormetic dose responses in a wide range of biological models, affecting numerous endpoints of biomedical and therapeutic significance. These responses were reported for numerous human tumor cell lines affecting breast, prostate, colon, lung, uterine and leukemia. In such cases, low concentrations of resveratrol enhanced tumor cell proliferation whereas higher concentrations were inhibitory.
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