Depth probing of diffuse tissues controlled with elliptically polarized light.

J Biomed Opt

Institut Fresnel, CNRS, Aix-Marseille Université, Ecole Centrale Marseille, Campus de Saint Jérôme, 13013 Marseille, France.

Published: January 2013

Polarization gating is a popular technique in biomedical optics. It is widely used to inspect the surface of the tissues (under colinear or cocircular detection) or instead to probe the volume (cross-linear detection), without information on the probed depth. Elliptical polarization is introduced to explore the possibility of probing diffuse tissues at selective depths. A thorough Monte Carlo simulation study shows complete correlation between the probed depths and the ellipticity of the polarized light, for a medium with known optical properties. Within a wide range of optical parameters, a linear relation between the backscattered intensity and the depth extension of the probed volume was found whatever the polarization used, but with a controlled extension depending on the ellipticity.

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http://dx.doi.org/10.1117/1.JBO.18.1.016007DOI Listing

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