Pd-catalysed direct dehydrogenative carboxylation of alkenes: facile synthesis of vinyl esters.

Chem Commun (Camb)

Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China.

Published: February 2013

A novel Pd-catalysed oxidative coupling reaction methodology using readily available carboxylic acids and alkenes for the preparation of vinyl esters has been developed. A broad range of vinyl esters were successfully synthesised. The reactions have demonstrated good efficiency as well as excellent chemo- and regio-selectivity.

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Source
http://dx.doi.org/10.1039/c2cc37779aDOI Listing

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