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Spatiotemporal profiles and underlying mechanisms of the antibiotic resistome in two water-diversion lakes.
Environ Res
December 2024
State Key Joint Laboratory of Environmental Simulation and Pollution Control, College of Environmental Sciences and Engineering, Peking University, Beijing, 100871, China. Electronic address:
Article Synopsis
- Human activities have changed lake ecosystems, affecting how antibiotic resistance genes (ARGs) behave in these environments, especially in water-diversion lakes like Nansi and Dongping.
- A study identified 653 ARG subtypes in these lakes, indicating seasonal changes, the influence of human modifications, and the presence of harmful bacteria linked to multidrug resistance.
- Key findings highlight that seasonal factors such as pH and temperature significantly impact bacterial communities and ARG profiles, emphasizing the need for better understanding and management of these water systems.
Application of LAMP assay for detection of carbapenem-resistant Acinetobacter calcoaceticus-Acinetobacter baumannii complex in ICU admitted sepsis patients: A rapid and cost-effective diagnostic tool.
Diagn Microbiol Infect Dis
September 2024
Department of Microbiology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi 110029, India. Electronic address:
Carbapenem-resistant significant members of Acinetobacter calcoaceticus-Acinetobacter baumannii (CR-SM-ACB) complex have emerged as an important cause of sepsis, especially in ICUs. This study demonstrates the application of loop-mediated-isothermal-amplification (LAMP) assay for detection of CR-SM-ACB-complex from patients with sepsis. Whole-blood and culture-broths(CB) collected from patients with culture-positive sepsis were subjected to LAMP and compared with PCR, and RealAmp.
View Article and Find Full Text PDFEvidence and antibiotic resistance profiles of clinical Acinetobacter calcoaceticus-Acinetobacter baumannii (ACB) and non-ACB complex members in companion animals: A 2020-2022 retrospective study.
Comp Immunol Microbiol Infect Dis
June 2024
Department of Veterinary Medicine and Animal Production, University of Naples "Federico II", Via F. Delpino n. 1, Naples 80137, Italy.
To evaluate the frequency of Acinetobacter spp., belonging to both Acinetobacter calcoaceticus-baumannii (ACB) and non-ACB complex, and their antibiotic resistance profiles in veterinary medicine, a three-year (2020-2022) retrospective study was carried out on sick companion animals. Epidemiological data from different clinical canine, feline, and equine samples, were acquired.
View Article and Find Full Text PDFA bioinformatic approach to identify confirmed and probable CRISPR-Cas systems in the - complex genomes.
Front Microbiol
April 2024
Posgrado en Ciencias Biológicas, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico, Mexico.
Introduction: The complex, or Acb complex, consists of six species: , and . is the most clinically significant of these species and is frequently related to healthcare-associated infections (HCAIs). Clustered regularly interspaced short palindromic repeat (CRISPR) arrays and associated genes () constitute bacterial adaptive immune systems and function as variable genetic elements.
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