Living Letters is an adaptive game designed to promote children's combining of how the proper name sounds with their knowledge of how the name looks. A randomized controlled trial (RCT) was used to experimentally test whether priming for attending to the sound-symbol relationship in the proper name can reduce the risk for developing reading problems in the first two grades of primary education. A Web-based computer program with more intensive practice than could be offered by teachers affords activities that prompt young children to pay attention to print as an object of investigation. The study focused on a sub-sample of 110 five-year-old Dutch children from 15 schools seriously delayed in code-related knowledge. Outcomes support the need for early remedial computer programs, and demonstrate that, without a brief but intensive treatment, more children from the at-risk group lack the capacity to benefit from beginning reading instruction in the early grades. With an early intervention in kindergarten, children with code-related skills delays gained about half a standard deviation on standardized tests at the end of grade 2.
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http://dx.doi.org/10.1007/s11145-011-9328-5 | DOI Listing |
Pharmaceuticals (Basel)
December 2024
Amity Institute of Biotechnology, Amity University Maharashtra, Mumbai 410206, Maharashtra, India.
: The global AIDS pandemic highlights the urgent need for novel antiretroviral therapies (ART). In our previous work, Zinc C295 was identified as a potent HIV-1 integrase strand transfer (ST) inhibitor. This study explores its potential to also inhibit 3'-processing (3'P), thereby establishing its dual-targeting capability.
View Article and Find Full Text PDFInt J Mol Sci
January 2025
Department of Mathematical, Physical and Computer Sciences, University of Parma, 43124 Parma, Italy.
This study presents an efficient and environmentally sustainable synthesis of ZnO nanoparticles using a starch-mediated sol-gel approach. This method yields crystalline mesoporous ZnO NPs with a hexagonal wurtzite structure. The synthesized nanoparticles demonstrated remarkable multifunctionality across three critical applications.
View Article and Find Full Text PDFJ Ethnopharmacol
January 2025
Phytomedicine Programme, Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, 0110, Pretoria, South Africa. Electronic address:
Ethnopharmacological Relevance: Zimbabwe is a key biodiversity domain in sub-Saharan Africa and ethnoveterinary medicines play an integral role in livestock health. However, knowledge on whether plants are used by only a small proportion of people or whether similar uses exist in different communities and in a more regional context is incompletely documented.
Aim Of The Study: Firstly, the study documented plant-based complementary medicines used for managing goat ailments.
PLoS One
January 2025
Faculty of Environmental Engineering, The University of Kitakyushu, Kitakyushu, Japan.
Petroleum hydrocarbon pollution causes significant damage to soil, so accurate prediction and early intervention are crucial for sustainable soil management. However, traditional soil analysis methods often rely on statistical methods, which means they always rely on specific assumptions and are sensitive to outliers. Existing machine learning based methods convert features containing spatial information into one-dimensional vectors, resulting in the loss of some spatial features of the data.
View Article and Find Full Text PDFWater Environ Res
January 2025
Zhejiang Key Laboratory of Petrochemical Environmental Pollution Control, Zhejiang Ocean University, Zhoushan, P. R. China.
Ocean oil spills can severely impact ecosystems and disrupt marine biodiversity and habitats. Microbial remediation is an effective method for removing thin oil slick contamination. In this study, the adsorption and degradation of low-concentration oil spills by Chlorella vulgaris LH-1 immobilized in konjac glucomannan (KGM) aerogel were investigated.
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