Perspectives of hyperpolarized noble gas MRI beyond 3He.

J Magn Reson

University of Nottingham, School of Clinical Sciences, Sir Peter Mansfield Magnetic Resonance Centre, Nottingham NG7 2RD, United Kingdom.

Published: April 2013

AI Article Synopsis

  • NMR studies with hyperpolarized noble gases explore the intersection of physics, chemistry, materials science, and biomedical applications.
  • The paper emphasizes the use of hyperpolarized (129)Xe in MRI, highlighting its current practical use and future potential for various medical and research applications.
  • Additionally, the discussion includes the emerging possibilities for surface-sensitive imaging using hyperpolarized (83)Kr.

Article Abstract

Nuclear Magnetic Resonance (NMR) studies with hyperpolarized (hp) noble gases are at an exciting interface between physics, chemistry, materials science and biomedical sciences. This paper intends to provide a brief overview and outlook of magnetic resonance imaging (MRI) with hp noble gases other than hp (3)He. A particular focus are the many intriguing experiments with (129)Xe, some of which have already matured to useful MRI protocols, while others display high potential for future MRI applications. Quite naturally for MRI applications the major usage so far has been for biomedical research but perspectives for engineering and materials science studies are also provided. In addition, the prospects for surface sensitive contrast with hp (83)Kr MRI is discussed.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3611600PMC
http://dx.doi.org/10.1016/j.jmr.2012.11.014DOI Listing

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