A system of microtests, adapted for pediatric practice, has been developed, tested, and proposed for practical use. The system includes 13 microtests, 4 of them meet the requirements of a rapid diagnostic test, the others are used as differentiating and specifying. For the first time three levels of the coagulation status have been distinguished in the newborn: physiologic, border and pathologic; this enables orientation in hemorrhagic and thrombohemorrhagic diseases in the newborn. On the basis of the unified microtests the authors have determined the tactics in early diagnosis and follow-up of newborns suffering from hemorrhage treated outpatiently. The diagnosis was verified under dispensary conditions in 158 (66.6%) children with hemorrhagic diathesis. The results of the investigations described are promising for further improvement of the diagnosis and treatment of hemostasis disorders in newborns with the use of the microtests of new generation.
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Bioengineering (Basel)
December 2024
Petroleum Refining Engineering and Environmental Protection Department, Faculty of Petroleum Refining and Petrochemistry, Petroleum-Gas University of Ploiesti, 100680 Ploiesti, Romania.
Knowledge of the impact of chemicals on the environment is important for assessing the risks that chemicals can generate in ecosystems. With the help of pilot-scale micro-tests, it was possible to evaluate the biological sludge in terms of its chemical and biological composition, information that can be applied on an industrial scale in treatment plants. The important parameters analyzed in the evaluation of the biodegradability of wastewater were pH, chemical composition (NH, NO, NO, and PO), dry substance (DS), inorganic substance (IS), and organic substance (OS), and the biological oxygen demand (BOD)/chemical oxygen consumption (COD) ratio.
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
November 2024
Medical College of Optometry and Ophthalmology, Shandong University of Traditional Chinese Medicine, Jinan, China.
Purpose: This study aims to investigate the effect of quercetin (QUE) on scleral remodeling by inhibiting the PERK-EIF2α signaling pathway and to evaluate its potential role in slowing myopia.
Methods: Lens-induced myopia (LIM) guinea pigs were obtained and treated with QUE. After 4 and 6 weeks of treatments, ocular biological measurements were conducted.
J Environ Sci (China)
February 2025
SZU-HKUST Joint PhD Program in Marine Environmental Science, Shenzhen University, Shenzhen 518060, China; Shenzhen Key Laboratory of Marine Microbiome Engineering, Institute for Advanced Study, Shenzhen University, Shenzhen 518060, China. Electronic address:
Increasing nitrogen and phosphorus discharge and decreasing sediment input have made silicon (Si) a limiting element for diatoms in estuaries. Disturbances in nutrient structure and salinity fluctuation can greatly affect metal uptake by estuarine diatoms. However, the combined effects of Si and salinity on metal accumulation in these diatoms have not been evaluated.
View Article and Find Full Text PDFOne Health
June 2024
Sao Paulo State University - UNESP, School of Veterinary Medicine and Animal Science, Botucatu, Brazil.
Rabies is a contagious viral disease that can be easily transmitted by the saliva and brain/nervous system tissues of the infected animals, causing severe and fatal encephalitis in both animals and humans. Vaccination campaigns are crucial to combat and prevent rabies's spread in dogs and humans. The Modified Fuenzalida & Palicios vaccines have been widely used since the 70s and have proven effective in producing a solid serological response.
View Article and Find Full Text PDFTrop Life Sci Res
June 2023
Department of Biochemistry, Ahmadu Bello University, P.M.B 1069 Zaria, Kaduna State, Nigeria.
Malaria still remains a life-threatening parasitic disease with universal targets set for control and elimination. This study aimed to evaluate the antimalarial susceptibility of isolates and to selected antimalarial agents and column chromatographic subfractions of leaves extract and FTIR and GCMS of SF8. Trager and Jensen as well as World Health Organisation (WHO) standardised micro-test system methods were used to determine susceptibility on the patients' blood samples; Column chromatographic procedure was carried out to obtain 11 pooled fractions; FTIR and GCMS were used to determine functional groups and phytochemicals respectively.
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