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Three recent studies converged on a specific protein-protein interface between TPP1 and telomerase as being crucial for the regulation of both telomerase recruitment and processivity in mammalian cells. An equivalent interaction appears to exist in budding yeast, making this a nearly universal means of telomerase regulation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560596 | PMC |
| http://dx.doi.org/10.1038/nsmb.2483 | DOI Listing |
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