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Hemodynamic assessment of pre- and post-operative aortic coarctation from MRI. | LitMetric

AI Article Synopsis

  • Coarctation of the aorta (CoA) is a congenital heart defect leading to a significant narrowing of the aorta, typically located after the aortic arch.
  • Treatment options include surgical repair, stent implantation, and balloon angioplasty, with hemodynamic analysis done through cardiac catheterization to evaluate pressure gradients.
  • The paper introduces a non-invasive technique using Computational Fluid Dynamics and MR imaging to assess blood flow dynamics before and after surgery, demonstrating a strong correlation with traditional catheterization results in five CoA patients.

Article Abstract

Coarctation of the aorta (CoA), is a congenital defect characterized by a severe narrowing of the aorta, usually distal to the aortic arch. The treatment options include surgical repair, stent implantation, and balloon angioplasty. In order to evaluate the physiological significance of the pre-operative coarctation and to assess the post-operative results, the hemodynamic analysis is usually performed by measuring the pressure gradient (deltaP) across the coarctation site via invasive cardiac catheterization. The measure of success is reduction of the (deltaP > 20 mmHg) systolic blood pressure gradient. In this paper, we propose a non-invasive method based on Computational Fluid Dynamics and MR imaging to estimate the pre- and post-operative hemodynamics for both native and recurrent coarctation patients. High correlation of our results and catheter measurements is shown on corresponding pre- and post-operative examination of 5 CoA patients.

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Source
http://dx.doi.org/10.1007/978-3-642-33418-4_60DOI Listing

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