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Simultaneous lymph node involvement by Castleman disease and Kaposi sarcoma. | LitMetric

Simultaneous lymph node involvement by Castleman disease and Kaposi sarcoma.

Rev Bras Hematol Hemoter

Instituto de Pesquisa Clínica Evandro Chagas (IPE), Fiocruz Rio de Janeiro (RJ), Brazil.

Published: January 2013

AI Article Synopsis

Article Abstract

Both multicentric Castleman disease and Kaposi sarcoma are more frequently observed in HIV infected patients. The coexistence of these Human herpesvirus 8 related lesions, in the same tissue, has been observed, but literature reports are scant. On the other hand, the expression of HHV-8-LANA-1 is easily demonstrable by immunohistochemistry. This has been shown to be a powerful tool for the diagnosis of these entities. The aim of this report is to communicate our experience with a case of multicentric Castleman disease occurring in the setting of HIV infection, which demonstrated microscopic Kaposi sarcoma in the same lymph node during the pathological work-up.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521439PMC
http://dx.doi.org/10.5581/1516-8484.20110018DOI Listing

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