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A Toxicological and Ecotoxicological Assay Based on Mussel (Mytilus galloprovincialis) Hemocytes Motility.
J Vis Exp
December 2024
Department of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento; NBFC, National Biodiversity Future Center;
Hemocytes are the circulating immune-competent cells in bivalve mollusks and play a key role in several important functions of cell-mediated innate immunity. During the early stages of the immune response, hemocytes actively migrate to the site of infection. This inherent motility is a fundamental characteristic of these cells.
View Article and Find Full Text PDFMolding Quality and Biological Evaluation of a Two-Stage Titanium Alloy Dental Implant Based on Combined 3D Printing and Subtracting Manufacturing.
ACS Omega
December 2024
State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration & National Clinical Research Center for Oral Diseases & Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Department of Oral Implants, School of Stomatology, The Fourth Military Medical University, Xi'an 710032, Shaanxi, P. R. China.
Metal 3D printing has been used in the manufacturing of dental implants. Its technical advantages include high material utilization and the capacity to form arbitrarily complex structures. However, 3D printing alone is insufficient for manufacturing two-stage titanium implants due to the limited precision in printing titanium alloy parts.
View Article and Find Full Text PDFEvaluation of ovarian stiffness and its biological mechanism using shear wave elastography in polycystic ovary syndrome.
Sci Rep
January 2025
Department of Ultrasound, The Second Affiliated Hospital of Fujian Medical University, No. 34 North Zhongshan Road, Quanzhou, 362000, Fujian Province, China.
Article Synopsis
- Polycystic ovary syndrome (PCOS) is a common endocrine disorder characterized by various factors, and this study utilizes a noninvasive imaging technique called shear wave elastography (SWE) to assess ovarian stiffness in patients with PCOS.
- The research found that individuals with PCOS had significantly higher numbers of follicles, ovarian volume, and increased SWE measurements compared to healthy controls, identifying these factors as independent risk indicators for PCOS.
- Additionally, a rat model showed that increased ovarian stiffness was linked to fibrosis and changes in gene expression related to the ovarian structure, suggesting a biological connection between stiffness and the prevalence of PCOS.
A drop dispenser for simplifying on-farm detection of foodborne pathogens.
PLoS One
December 2024
Department of Agricultural and Biological Engineering, Purdue University, West Lafayette, Indiana, United States of America.
Nucleic-acid biosensors have emerged as useful tools for on-farm detection of foodborne pathogens on fresh produce. Such tools are specifically designed to be user-friendly so that a producer can operate them with minimal training and in a few simple steps. However, one challenge in the deployment of these biosensors is delivering precise sample volumes to the biosensor's reaction sites.
View Article and Find Full Text PDFFemtomolar hydrogen sulfide detection via hybrid small-molecule nano-arrays.
Nat Commun
December 2024
College of Engineering and Applied Sciences, Jiangsu Key Laboratory of Artificial Functional Materials, Nanjing University, Nanjing, China.
Early disease diagnosis hinges on the sensitive detection of signaling molecules. Among these, hydrogen sulfide (HS) has emerged as a critical player in cardiovascular and nervous system signaling. On-chip immunoassays, particularly nanoarray-based interfacial detection, offer promising avenues for ultra-sensitive analysis due to their confined reaction volumes and precise signal localization.
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