Introduction: Angiosarcomas are rare tumours that arise from the vascular endothelium. They can occur anywhere in the body, mostly affecting the head and neck. Their occurrence in the gastrointestinal tract is quite rare with a few reported cases in medical literature.
Presentation Of Case: A 40-year-old man presented with metastatic sigmoid colon angiosarcoma, for which he was operated due to endoscopically uncontrollable massive tumour bleeding. The patient is presently still alive at 24 months after his first presentation. He is receiving palliative care.
Discussion: This article presents a review of the literature on this rare clinical entity, emphasising the very aggressive behaviour and the poor outcome of this malignancy. We present, briefly, 17 reported cases on primary colonic angiosarcoma since 1949.
Conclusion: The role of chemotherapy and radiation is established neither in the adjuvant setting nor in metastatic disease. Surgery is the mainstay to treat localised colorectal angiosarcomas.
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http://dx.doi.org/10.1016/j.ijscr.2012.11.021 | DOI Listing |
ACG Case Rep J
August 2024
Department of Internal Medicine, Division of Digestive Diseases and Nutrition, University of South Florida, Morsani College of Medicine, Tampa, FL.
Epithelioid angiosarcoma is an aggressive form of angiosarcoma, and primary colonic tumors are extremely rare. We present the case of a 60-year-old man who presented with what initially appeared to be postpolypectomy bleeding. After undergoing repeat endoscopy, he was found to have epithelioid angiosarcoma of the transverse colon, and imaging further confirmed that it was the primary tumor site.
View Article and Find Full Text PDFRadiographics
April 2024
From the Department of Radiology, Hospital Universitari de Girona Doctor Josep Trueta, Av França S/N, 17007, Girona, Spain (A.R.A., N.C., S.J., A.H., V.P.); Department of Radiology, Hospital Clinic de Barcelona, Barcelona, Spain (B.D.X.); Department of Cardiology, Clinica Colon, Buenos Aires, Argentina (L.R.E.); and Division of Cardiothoracic Imaging, Department of Radiology, University of Colorado Anschutz Medical Campus, Aurora, Colo (D.V.).
Cureus
March 2023
Internal Medicine, University of Louisville School of Medicine, Louisville, USA.
Angiosarcoma is a rare mesenchymal tissue neoplasm, typically involving lymphatic or vascular endothelial cells. The tumor can arise anywhere in the body, though it is most often found as cutaneous lesions in the head and neck region. Due to its rarity, a diagnosis can sometimes be missed, especially when the sarcoma involves an uncommon site like the gastrointestinal tract.
View Article and Find Full Text PDFZhonghua Bing Li Xue Za Zhi
May 2023
Department of Pathology, Cancer Center, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China.
Mod Pathol
January 2023
Department of Pathology, The Ohio State University Wexner Medical Center, Columbus, Ohio. Electronic address:
Similar to PAX8, SOX17 was recently identified as a master transcription factor of ovarian cancer based on RNA sequencing data. We explored SOX17 utility in diagnosing ovarian tumors and other gynecologic tumors. We systematically evaluated SOX17 expression on tissue microarrays of 398 ovarian tumors of various types, 93 endometrial carcinomas, 80 cervical carcinomas, and 1371 nongynecologic carcinomas, such as those of kidney, thyroid, breast, colon, bladder, liver, bile duct, adrenal gland, pancreas, brain, and lung and malignant melanoma.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!