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Analysis of risk factors of infection in patients with inflammatory bowel disease.
Prz Gastroenterol
September 2024
Department of Internal Medicine and Gastroenterology with Inflammatory Bowel Disease Unit, National Medical Institute of the Ministry of Interior and Administration, Warsaw, Poland.
Introduction: infection (CDI) is one of the most important challenges in contemporary gastroenterology. However, data from CDI studies are sometimes contradictory.
Aim: To analyse the risk factors for CDI in patients with inflammatory bowel disease (IBD).
Background: Recent biomedical research has shown the unusual, multisystem effects of coronavirus disease 2019 in humans. One specific sequela of a primary severe acute respiratory syndrome coronavirus 2 infection is the reactivation of latent viruses in various tissues, such as Epstein-Barr virus. Epstein-Barr virus has been identified in many inflammatory gastrointestinal lesions, such as microscopic gastritides and colitides.
View Article and Find Full Text PDFA case description of collagenous gastritis concurrent with collagenous colitis: visible endoscopic changes.
Quant Imaging Med Surg
December 2024
Endoscopy Unit, The Second University Clinic, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Alleviation of Helicobacter pylori- or aspirin-induced gastritis and neuroinflammation in mice by Lactococcus lactis and Bifidobacterium longum.
Lett Appl Microbiol
December 2024
Neurobiota Research Center, College of Pharmacy, Kyung Hee University, 26, Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea.
Article Synopsis
- Helicobacter pylori (HP) is linked to gastritis and peptic ulcers, prompting a study on how probiotics Lactococcus lactis P135 and Bifidobacterium longum P142 can inhibit HP growth and the inflammatory response.
- Both probiotics significantly reduced HP levels, inflammation markers, and also improved symptoms like depression and cognitive impairment in mice suffering from HP-induced conditions.
- The administration of these probiotics resulted in beneficial changes in gut microbiota, with a decrease in harmful bacteria and an increase in beneficial ones, suggesting they could help reduce gut and neuroinflammation, thereby improving overall health.
IgA facilitates the persistence of the mucosal pathogen Helicobacter pylori.
Mucosal Immunol
November 2024
Institute of Molecular Cancer Research, University of Zürich, Zürich, Switzerland; Comprehensive Cancer Center Zürich, Zürich, Switzerland. Electronic address:
Article Synopsis
- IgA antibodies play a crucial role in defending against mucosal pathogens like Helicobacter pylori and Citrobacter rodentium, with strong local IgA responses observed during infections.
- The study shows that production of IgA involves various immune components, including Peyer's patches and specific T-cells, and is influenced by bacterial factors like type IV secretion systems.
- Interestingly, while IgA helps control H. pylori effectively, its absence leads to severe infections and weight loss with C. rodentium, highlighting that IgA's effects can vary depending on the pathogen involved.*
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