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Sinusitis caused by Exserohilum rostratum after cord blood transplantation for myelodysplastic syndrome: A case report and literature review.
Transpl Infect Dis
February 2018
Division of Hematology, Department of Medicine, Keio University Hospital, Tokyo, Japan.
Invasive fungal disease is a serious infectious complication of allogeneic hematopoietic stem cell transplantation (HSCT). Exserohilum rostratum is a species causing phaeohyphomycosis, which rarely causes invasive disease in humans. We treated a case of sinusitis caused by E.
View Article and Find Full Text PDFExserohilum infections associated with contaminated steroid injections: a clinicopathologic review of 40 cases.
Am J Pathol
September 2013
Infectious Diseases Pathology Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
September 2012 marked the beginning of the largest reported outbreak of infections associated with epidural and intra-articular injections. Contamination of methylprednisolone acetate with the black mold, Exserohilum rostratum, was the primary cause of the outbreak, with >13,000 persons exposed to the potentially contaminated drug, 741 confirmed drug-related infections, and 55 deaths. Fatal meningitis and localized epidural, paraspinal, and peripheral joint infections occurred.
View Article and Find Full Text PDFIatrogenic Exserohilum infection of the central nervous system: mycological identification and histopathological findings.
Mod Pathol
February 2013
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287-7093, USA.
Article Synopsis
- An outbreak of fungal infections has been linked to contaminated methylprednisolone acetate epidural injections, resulting in cases of meningitis and vasculitis in patients.
- In a specific case, an immunocompetent patient developed severe Exserohilum meningitis one week after receiving an injection for chronic neck pain, leading to brain and spinal cord damage.
- The report details the diagnostic methods used to identify the fungus E. rostratum and its associated histopathological findings, marking it as a significant case of iatrogenic fungal meningitis.
Invasive sinonasal disease due to dematiaceous fungi in immunocompromised individuals: case report and review of the literature.
Int J Infect Dis
September 2010
Department of Medicine, Division of Infectious Diseases, Virginia Commonwealth University Medical Center, 1101 East Marshall Street, Richmond, VA 23298-0049, USA.
Invasive dematiaceous fungal sinusitis is an uncommon and aggressive disease in immunocompromised individuals. We report a unique case of invasive Exserohilum sinusitis in a pregnant, immunocompromised woman. After treating the woman with pregnancy-induced aplastic anemia and invasive Exserohilum sinusitis and pulmonary disease, we performed a Medline/PubMed review of invasive dematiaceous fungal sinonasal disease in immunocompromised individuals.
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