A ciliated muconodular papillary tumor has been reported to be a peripheral low-grade malignant tumor, consisting of ciliated columnar cells and goblet cells with basaloid cell proliferation. Although ciliated muconodular papillary tumors have not yet been classified according to the World Health Organization classification, they can pose diagnostic and therapeutic problems. Here we report a resected case of ciliated muconodular papillary tumor with computed tomography findings reminiscent of adenocarcinoma, showing a small irregular nodule adjacent to the intersegment pulmonary vein. There was no uptake of F-18 fluorodeoxyglucose positron emission tomography. The patient underwent surgical resection, and a lobectomy was performed because intraoperative needle biopsy suggested neoplastic proliferation. No EGFR mutations were detected. No recurrence was noted during 24-month follow-up after lobectomy.
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http://dx.doi.org/10.1093/jjco/hys218 | DOI Listing |
Thorac Cancer
October 2024
Department of Thoracic Surgery, Bahçeşehir University, Istanbul, Turkey.
Bronchiolar adenoma (BA)/ciliated muconodular papillary tumor (CMPT) is a rare pulmonary neoplasm, with less than 150 cases documented in the literature. We report a unique case of BA/CMPT complicated by lymphoid interstitial pneumonia (LIP) in a 55-year-old male with Sjögren's disease. This is the first documented instance of such a comorbidity.
View Article and Find Full Text PDFArch Pathol Lab Med
May 2024
From the Department of Pathology, Cleveland Clinic, Cleveland Ohio.
Context.—: Intraoperative (frozen section) analysis of lung lesions (nodules, masses, ground-glass opacities) can occasionally be diagnostically challenging.
Objective.
Thorac Cancer
June 2024
Department of General Thoracic Surgery, Saitama Medical University International Medical Center, Hidaka, Japan.
Solitary pulmonary papillomas (SPPs) are rare lung neoplasms. Histologically, SPP is classified into three subtypes, and mixed squamous and glandular papilloma (MP) is the rarest subtype. Although SPPs are considered benign tumors, there have been several reports on the synchronous malignant transformation in SPPs.
View Article and Find Full Text PDFInt J Surg Pathol
October 2024
Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai, China.
Ciliated muconodular papillary tumor (CMPT) is a rare pulmonary tumor, typically occurring in middle-aged and elderly individuals. The molecular mutation spectrum of CMPT remains insufficiently explored. Commonly known driver gene alterations include , , , and rearrangement.
View Article and Find Full Text PDFMedicine (Baltimore)
December 2023
Department of Radiology, Weifang No. 2 People's Hospital, Shandong Province, China.
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