AI Article Synopsis
- Serine Protease Inhibitors (Serpins) are crucial in human health and are a significant focus for biomedical research and treatment of various diseases.
- Recent research has led to the discovery of new serpin-encoding genes across different life forms, despite these genes showing low sequence similarities.
- Future studies are expanding beyond protease inhibition to explore how serpins interact with other molecules, including hormone transport, and new patents in this area are emerging.
Article Abstract
The Serine Protease Inhibitors (Serpins) have been a focus of research by biomedical industries due to their critical role in human health. The use of serpin in the treatment of many diseases was widely investigated through the identification of new genes encoding these proteins in all kingdoms of life. The characterization of these genes revealed that they encoded proteins having low sequence homologies. Future developments are focusing not only on the protease inhibition activity, but also on the other effects due to the interactions of serpins with other components such as hormone transport. Here we give a concise overview of the most recent patents that have been reported in this field of research.
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| http://dx.doi.org/10.2174/1872215611307020008 | DOI Listing |
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