Objective: The aim of this in-vivo study was to evaluate the 2-year clinical performance of zirconia computer-aided design/computer-aided manufacturing (CAD/CAM)-generated bridges.
Methods: A total of 16 three- or four-unit Lava zirconia bridges were done on 15 subjects. The bridges were cemented using RelyX™ Unicem Self-Adhesive Universal Resin Cement. Evaluation was done at 6-month, 1-year, and 2-year recall visits. Evaluation criteria were color stability and matching, marginal integrity, marginal discoloration, incidence of caries, changes in restoration-tooth interface, changes in surface texture, postoperative sensitivity, maintenance of periodontal health, changes in proximal and opposing teeth, and maintenance of anatomic form. In each of these parameters, the bridges were rated in one of three possible categories: "A" (alpha)--ideal; "B" (bravo)--acceptable; and "C" (charlie)--unacceptable.
Results: After 2 years, 100% of the bridges were rated "A" for color stability and matching, marginal discoloration, incidence of caries, changes in restoration-tooth interface, changes in surface texture, postoperative sensitivity, and change in proximal or opposing teeth. In the parameter of marginal integrity, 6.25% of the bridges were rated "B;" the remaining 93.75% were rated "A." Maintenance of periodontal health was rated "B" for 6.25% of the bridges and "A" for 93.75%. At 2 years, 12.5% of the bridges rated "C" in maintenance of anatomic form and 87.5% rated "A."
Conclusion: The overall clinical outcome was that the CAD/CAM-generated zirconia bridges were clinically acceptable.
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Am J Clin Pathol
January 2025
Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC, US.
Objectives: Social media platforms like Facebook, X (formally Twitter), and Instagram bridge pathology programs with other health professionals, prospective students, and the public, but the extent of social media usage by residency programs remains unexplored. This study investigates the current landscape of social media utilization by pathology programs.
Methods: Using the National Resident Matching Program (NRMP) Match Data from 2022, 139 anatomic and clinical pathology residency programs were analyzed and categorized into 3 prestige tiers based on Doximity ratings.
J Subst Use Addict Treat
January 2025
University of Missouri, Department of Psychological Sciences, 210 McAlester Hall, Columbia, MO 65211, United States of America.
Introduction: Although there are evidence-based strategies (EBSs) for alcohol and other drug (AOD) prevention and treatment for college students, there has been little focus on evaluating AOD EBS implementation in higher education. The use of implementation strategies in higher education may help bridge the gap between research and practice and improve students' access to EBSs. However, it is important to first understand determinants of AOD EBS program implementation to support AOD EBS selection and implementation strategy selection.
View Article and Find Full Text PDFNat Med
January 2025
Google Research, Mountain View, CA, USA.
Large language models (LLMs) have shown promise in medical question answering, with Med-PaLM being the first to exceed a 'passing' score in United States Medical Licensing Examination style questions. However, challenges remain in long-form medical question answering and handling real-world workflows. Here, we present Med-PaLM 2, which bridges these gaps with a combination of base LLM improvements, medical domain fine-tuning and new strategies for improving reasoning and grounding through ensemble refinement and chain of retrieval.
View Article and Find Full Text PDFIISE Trans Occup Ergon Hum Factors
January 2025
The Polytechnic School, Arizona State University, Mesa, AZ, USA.
OCCUPATIONAL APPLICATIONSResults from our exploratory study of restaurant worker mental models of injury and safety emphasize the need for improved occupational safety in the culinary industry through targeted interventions for chefs and managers. The analysis we performed showed that managers possess more integrated and coherent mental models of injury and safety than chefs, reflected in network parameters showing better organization of safety concepts. Kitchen training programs should focus on bridging gaps in safety awareness and mitigating hazards such as burns, cuts, slips, and equipment-related risks.
View Article and Find Full Text PDFBMC Glob Public Health
January 2025
Division of General Internal Medicine, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, 80045 CO, USA.
Background: In the USA, many states, including Colorado, have increased criminal penalties for illicit opioid possession, which may alter overdose risk. We aimed to evaluate the relationship between Colorado's increased drug-related criminal legal penalties, risk of overdose, and substance use patterns.
Methods: We used concept mapping - a mixed-methods approach used to develop a conceptual understanding of an issue from a community lens - to engage with people with living and/or lived experience with the criminal legal system, substance use, and/or overdose, their loved ones, and service providers.
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