Summary of and comment on a recent paper entitled ‘Gene sets identified with oncogene cooperativity analysis regulate in vivo growth and survival of leukemia stem cells’ (Ashton et al., 2012).
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529332 | PMC |
| http://dx.doi.org/10.1242/dmm.011288 | DOI Listing |
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Initial Validation of the Mandarin Translation of the Stanford Social Dimensions Scale (SSDS).
J Autism Dev Disord
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Aspect Research Centre for Autism Practice, Autism Spectrum Australia, Level 5, Tower B, The Zenith, 821 Pacific Highway, Chatswood, NSW, 2067, Australia.
This study aimed to validate the Mandarin translation of the Stanford Social Dimensions Scale (SSDS). The initial validation sample consisted of 480 children with Autism Spectrum Disorder (ASD) (M = 9.35).
View Article and Find Full Text PDFMechanisms and clinical applications of palmitoylethanolamide (PEA) in the treatment of neuropathic pain.
Inflammopharmacology
December 2024
Department of Research and Development, First Floor, Molecules Biolabs Private Limited, Commercial Building Kinfra, 3/634Konoor Road, Muringur, Vadakkummuri, Koratty, Mukundapuram, Thrissur, Kerala, 680309, India.
Palmitoylethanolamide (PEA) is emerging as a promising therapeutic agent for neuropathic and other pain-related conditions. This naturally occurring fatty acid has drawn interest because of its ability to regulate pain and inflammation. Initially identified in food sources, PEA has been the subject of extensive research to elucidate its properties, efficacy, and clinical applications.
View Article and Find Full Text PDFQuasi-One-Dimensional Spin Dynamics in a Molecular Spin Liquid System.
Phys Rev Lett
December 2024
RIKEN Cluster for Pioneering Research, Wako, Saitama 351-0198, Japan.
The molecular triangular lattice system, β^{'}-EtMe_{3}Sb[Pd(dmit)_{2}]_{2}, is considered as a candidate material for the quantum spin liquid state, although ongoing debates arise from recent controversial results. Here, the results of electron spin resonance and muon-spin relaxation measurements on β^{'}-EtMe_{3}Sb[Pd(dmit)_{2}]_{2} are presented. Both results indicate characteristic behaviors related to quasi-one-dimensional spin dynamics, whereas the direction of anisotropy found in electron spin resonance is in contradiction with previous theories.
View Article and Find Full Text PDFAn AI dose-influence matrix engine for robust pencil beam scanning protons therapy.
Med Phys
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National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.
Background: Rapid planning is of tremendous value in proton pencil beam scanning (PBS) therapy in overcoming range uncertainty. However, the dose calculation of the dose influence matrix (D) in robust PBS plan optimization is time-consuming and requires substantial acceleration to enhance efficiency.
Purpose: To accelerate the D calculations in PBS therapy, we developed an AI-D engine integrated into our in-house treatment planning system (TPS).
Medicare Advantage Population in the United States: Outcomes of Patients with Asthma Treated with ICS/LABA Before and After Initiation with Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI).
Adv Ther
December 2024
US Value Evidence and Outcomes, GSK, Collegeville, PA, USA.
Introduction: The clinical benefits of fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) have been demonstrated in clinical trials. There is limited evidence regarding the effectiveness and economic outcomes associated with FF/UMEC/VI use in US clinical practice. This real-world study assessed asthma-related exacerbations, healthcare resource utilization (HRU), and healthcare costs among a Medicare Advantage-insured population before and after initiation of FF/UMEC/VI in patients with asthma previously treated with an inhaled corticosteroid/long-acting β-agonist (ICS/LABA).
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