The objective of the present work was to study the principal causative agents of acute bacterial rhinosinusitis (ABRS) and the mechanisms underlying the development of its relapses. The secondary objective was to consider problems related to the antibacterial treatment of this pathology and suggest approaches to their solution. The results of analysis of the causes behind relapses of acute bacterial rhinosinisitis are presented, the recommendations on the choice of antibacterial preparations are proposed.

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