The patient is a 42-year-old man who is a Jehovah's Witness. For the duodenal gastrointestinal stromal tumor, duodenal segmental resection and a duodenal jejunum anastomosis were indicated. He took imatinib for 2 years after the operation. After 8 months, recurrent multiple liver metastases were found at S2-3 and S7, which were in contact with the inferior vena cava. Excessive intraoperative bleeding was expected. The patient hoped that a blood transfusion operation would not be required. He took sunitinib to reduce the size of the tumor, and the tumor had become smaller after 8 months. It was possible to resect the tumor without a blood transfusion. The patient has been on imatinib since 1 month after the operation. No recurrence was detected within 1 year of the operation.

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