AI Article Synopsis
- The analysis reviewed 20 cases of metastatic liver cancer treated with stereotactic radiotherapy (SRT), which showed a response rate of 78%.
- The treatment involved 52.8 Gy delivered in 4 fractions over 1 week, achieving complete or partial responses in 18 out of 27 therapeutic sites.
- The findings suggest that the best candidates for SRT are patients with a single liver nodule and no spread of cancer outside the liver, particularly those who have already received systemic chemotherapy.
Article Abstract
Twenty cases (27 therapeutic sites/30 nodules) of metastatic liver cancer treated with stereotactic radiotherapy (SRT)were analyzed. The original sites of cancer were colorectal(8 cases), breast(4 cases), stomach(3 cases), esophagus(2 cases), and other organs (3 cases). SRT was performed with 52.8 Gy·4 fr·-1·wk-1. The response rate was 78%, including complete response (CR) at 8 sites, partial response (PR) at 10 sites, stable disease (SD) at 2 sites, progressive disease(PD) at 3 sites, and not detected(ND) at 4 sites, thus demonstrating a potent local therapeutic effect. Ten patients survived for more than 1 year, 8 patients survived for 2 years, and 4 died before 6 months. Clinical analysis suggests that the ideal indications for SRT are patients with a solitary nodule and without extrahepatic disease who have undergone systemic chemotherapy.
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