AI Article Synopsis
- The study involved 168 patients with advanced or recurrent breast cancer who received hyperthermia or immunotherapy after standard treatments failed or were declined.
- Clinical benefits were seen in 26 patients, with complete responses occurring in 4 cases.
- The combination of hyperthermia with immunotherapy significantly improved effectiveness, especially in 20 patients with distant metastases to solid organs.
Article Abstract
We treated 168 advanced or recurrent breast cancer patients with hyperthermia or immunotherapy (2005/7-2011/12). In these cases, standard therapy showed no effect or was refused. Clinical benefit( complete response: CR, partial response, and long stable disease) was observed in 26 cases; CR occurred in 4 cases. The effective rate of immunotherapy increased from 9.1% to 23.9% using hyperthermia. Both hyperthermia and immunotherapy needed to be used together to be effective in 20 cases with distant metastases to solid organs.
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